Human Biology Open Access Pre-Prints

 

Human Biology is committed to fostering cooperation among anthropological geneticists, and so makes available open access pre-prints of many of the articles it publishes. The following pre-prints represent scholarship to be published in future volumes of Human Biology, as well as archival pre-print versions of scholarship previously published.

About Human Biology

Founded in 1929,Human Biology is an international, peer-reviewed journal that focuses on research to increase understanding of human biological variation. Among the topics considered by the journal are anthropological, quantitative, evolutionary, and population genetics and genomics; ancient DNA studies and paleogenomics; demography and genetic epidemiology; and ethical and social implications of human genetic and genomic research.

Human Biology is the official publication of the American Association of Anthropological Genetics (AAAG), an educational and scientific organization founded in 1994. AAAG aims to promote the study of anthropological genetics, as this field is broadly defined, to facilitate communication between individuals engaged in the study of anthropological genetics and to foster cooperation among anthropological geneticists.

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Submissions from 2017

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Infectious Disease and the Diversification of the Human Genome (Vol. 89, Iss. 1), Jessica F. Brinkworth

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Population History and Mitochondrial Genetic Substructure of the Rama Amerindians from Nicaragua (Vol. 88, Iss. 2), Norberto F. Baldi and Michael H. Crawford

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The Fortieth Anniversary of the Founding of the Laboratory of Biological Anthropology (Vol. 88, Iss. 2), Michael H. Crawford

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Piecewise Regression Analysis of Secular Change in the Maximum Femoral Vertical Head Diameter of American White Males and Females (Vol. 88, Iss. 1), Sandra Cridlin

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Isonymic Relations In The Bolivia-Argentina Border (Vol. 88, Iss. 3), José Edgardo Dipierri, Emma Laura Alfaro Gomez, Alvaro Rodríguez-Larralde, and Virginia Ramallo

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Y chromosome haplogroups in the Bosnian-Herzegovinian population based on 23 Y-STR loci (Vol. 88, Iss. 3), Serkan Dogan, Adna Ašić, Gulsen Dogan, Larisa Besic, and Damir Marjanovic

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Modelling Demic and Cultural Diffusion - An Introduction (Vol. 87, Iss. 3), Joaquim Fort, Enrico R. Crema, and Marco Madella

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Jujuy Province (NW Argentina): STR Markers Unveil Microgeographic Differentiation Over a Steep Mountainous Landscape (Vol. 88, Iss. 3), Luis Gómez-Pérez, Miguel A. Alfonso-Sánchez, José Edgardo Dipierri, and Jose A. Pena

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Genetic structure of First Nation communities in the Pacific Northwest (Vol. 88, Iss. 4), Cris E. Hughes, Mary P. Rogers, Amanda C. Owings, Barbara Petzelt, Joycelynn Mitchell, Harold Harry, Theresa Williams, Dena Goldberg, Damian Labuda, David Glenn Smith, Jerome S. Cybulski, and Ripan S. Malhi

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Beyond Serial Founder Effects: The Impact of Admixture and Localized Gene Flow on Patterns of Regional Genetic Diversity (Vol. 88, Iss. 3), Keith Hunley and Graciela S. Cabana

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Secular Changes in the Postcranial Skeleton of American Whites (Vol. 88, Iss. 1), Richard L. Jantz, Lee Meadows Jantz, and Joanne L. Devlin

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Finding Rare, Disease-Associated Variants in Isolated Groups: Potential Advantages of Mennonite Populations (Vol. 88, Iss. 2), Fabiana L. Lopes, Liping Hou, Angelica B. W. Boldt, Layla Kassem, Veronica M. Alves, Antonio E. Nardi, and Francis J. McMahon

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Patterns Of DNA Methylation Across the Leptin Core Promoter in Four Diverse Asian and North American Populations (Vol. 88, Iss. 2), M. J. Mosher, P. E. Melton, P. Stapleton, M. S. Schanfield, and M. H. Crawford

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An Attempt to Integrate Previous Localized Estimates of Human Inbreeding for the Whole of Britain (Vol. 88, Iss. 4), John E. Pattison

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X-chromosome Alu Insertions in Bahía Blanca (Argentina): assessment of population information from varied genetic markers and usefulness of X-chromosome markers to trace sex-biased parental contributions (Vol. 88, Iss. 4), Magdalena Resano, Daniela Zanetti, Esther M. Esteban, and Pedro Moral

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Genetic Evidence for Modifying Oceanic Boundaries Relative to Fiji (Vol. 88, Iss. 3), Gerhard P. Shipley, Diana A. Taylor, Antoine D. R. N’Yeurt, Anand Tyagi, Geetanjali Tiwari, and Alan J. Redd

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Craniofacial Secular Change in Recent Mexican Migrants (Vol. 88, Iss. 1), Katherine Spradley, Kyra E. Stull, and Joseph T. Hefner

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Landscape Complexity in the Caucasus impedes Genetic Assimilation of Human Populations More Effectively than Language or Ethnicity (Vol. 88, Iss. 4), David Tarkhnishvili, Alexander Gavashelishvili, Marine Murtskhvaladze, and Ardashel Latsuzbaia

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An Examination of the Differential Effects of the Modern Epidemiological Transition on Cranial Morphology in the United States and Portugal (Vol. 88, Iss. 1), Katherine E. Weisensee and Richard L. Jantz

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Secular Change in the Femur Diaphyseal Biomechanical Properties of American Whites (Vol. 88, Iss. 1), Daniel J. Wescott and Lauren Rockhold Zephro

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Mitochondrial-DNA Phylogenetic Information and the Reconstruction of Human Population History: The South American Case (Vol. 89, Iss. 3), María Bárbara Postillone and S. Ivan Perez

Submissions from 2016

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Ancient DNA Investigation of a Medieval German Cemetery Confirms Long-Term Stability of CCR5-∆32 Allele Frequencies in Central Europe (Vol. 89, Iss. 2), Abigail Bouwman, Natallia Shved, Gulfirde Akgul, Frank Ruhli, and Christina Warinner

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A Mainly Circum-Mediterranean Origin for West Eurasian and North African mtDNAs in Puerto Rico with Strong Contributions from the Canary Islands and West Africa (Vol. 89, Iss. 2), Héctor J. Díaz-Zabala, María A. Nieves-Colón, and Juan C. Martínez-Cruzado

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Extending genome-wide association study (GWAS) results to test classic anthropological hypotheses: Human third molar agenesis and the ‘probable mutation effect’ (Vol. 89, Iss. 2), Alexis Sullivan, Adrijana Vukelic, Jacob Cohen, and George (PJ) Perry

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The genomic health of ancient hominins (Vol. 89, Iss. 1), Ali J. Berens, Taylor L. Cooper, and Joseph Lachance

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Admixture and ancestry inference from ancient and modern samples through measures of population genetic drift (Vol. 89, Iss. 1), Alexandre M. Harris and Michael DeGiorgio

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The multiple histories of Western Asia: Perspectives from ancient, and modern genomes (Vol. 89, Iss. 1), Recep Taskent and Omer Gokcumen

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Paternal Genetic Structure In Contemporary Mennonite Communities From The American Midwest (Vol. 88, Iss. 2), Kristine G. Beaty, M. J. Mosher, Michael H. Crawford, and Phillip Melton

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Genetic Affiliation of Pre-Hispanic and Contemporary Mayas through Maternal Linage (Vol. 88, Iss. 2), Mirna Isabel Ochoa-Lugo, Maria de Lourdez Muñoz, Gerardo Pérez-Ramírez, Kristine G. Beaty, Mauro López-Armenta, Javiera Cervini-Silva, Miguel Moreno-Galeana, Adrián Martínez Meza, Eduardo Ramos, Michael H. Crawford, and Arturo Romano-Pacheco

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Changes in Clavicle Length and Maturation in Americans: 1840–1980 (Vol. 88, Iss. 1), Natalie R. Langley and Sandra Cridlin

Submissions from 2015

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Racial Experience as an Alternative Operationalization of Race (Vol. 87, Iss. 4), Jada Benn Torres and Gabriel A. Torres Colón

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Interaction of Alu Polymorphisms and Novel Measures of Discrimination in Association with Blood Pressure in African Americans Living in Tallahassee (Vol. 87, Iss. 4), Alexis C. Boulter, Jackyn Quinlan, Aida T. Miró-Herrans, Laurel N. Pearson, Nubiana L. Todd, Clarence C. Gravlee, and Connie J. Mulligan

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So You Think You Can Model? A Guide to Building and Evaluating Archaeological Simulation Models of Dispersals (Vol. 87, Iss. 3), Iza Romanowska

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Case Study on Ancestry Estimation in an Alaskan Native Family: Identity and Safeguards against Reductionism (Vol. 87, Iss. 4), Alyssa C. Bader and Ripan S. Malhi

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Combating Racial Health Disparities through Medical Education: The Need for Anthropological and Genetic Perspectives in Medical Training (Vol. 87, Iss. 4), Deborah A. Bolnick

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Cultural Incubators and Spread of Innovation (Vol. 87, Iss. 3), Enrico R. Crema and Mark W. Lake

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A General Model of the Relationship between the Apportionment of Human Genetic Diversity and the Apportionment of Human Phenotypic Diversity (Vol. 87, Iss. 4), Michael D. Edge and Noah A. Rosenberg

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The Evolution of Tanning Needs Its Day in the Sun (Vol. 87, Iss. 4), Ellen E. Quillen

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Productivity of Pre-Modern Agriculture in the Cucuteni-Trylillia Area (Vol. 87, Iss. 3), Anvar Shukurov, Mykhailo Videiko, Graeme Sarson, Kate Henderson, Robert Shiel, Pavel Dolukhanov, and Galina Pashkevich

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Inference of Cultural Transmission Modes Based on Incomplete Information (Vol. 87, Iss. 3), Bryan Wilder and Anne Kandler

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Does Environmental Knowledge Inhibit Hominin Dispersal? (Vol. 87, Iss. 3), Colin D. Wren and Andre Costopoulos

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Evolution and Otitis Media: A Review, and a Model to Explain High Prevalence in Indigenous Populations (Vol. 87, Iss. 2), Mahmood F. Bhutta

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Mongolians in the Genetic Landscape of Central Asia: Exploring the Genetic Relations among Mongolians and Other World Populations (Vol. 87, Iss. 2), Jane E. Brissenden, Judith R. Kidd, Baigalmaa Evsanaa, Ariunaa Togtokh, Andrew J. Pakstis, Françoise Friedlaender, Kenneth K. Kidd, and Janet M. Roscoe

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Origins of an Unmarked Georgia Cemetery Using Ancient DNA Analysis (Vol. 87, Iss. 2), Andrew T. Ozga; Raúl Y. Tito; Brian M. Kemp; Hugh Matternes; Alexandra Obregon-Tito; Leslie Neal; and Cecil M. Lewis, Jr.

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Influence of Changes in Political Barriers and of Geographic Distance on Kinship Inferred from Surnames and Migration Data in Olivenza (Spain) and Surrounding Portuguese Areas (Vol. 87, Iss. 2), J. Román-Busto

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A Cultural Diffusion Model for the Rise and Fall of Programming Languages (Vol. 87, Iss. 2), Sergi Valverde and Ricard V. Solé

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Low Mitochondrial DNA Diversity in an Ancient Population from China: Insight (Vol. 87, Iss. 1), Yu Dong, Chunxiang Li, Fengshi Luan, Zhenguang Li, Hongjie Li, Yinqiu Cui, Hui Zhou, and Ripan S. Malhi

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Genetic Admixture and Flavor Preferences: Androstenone Sensitivity in Malagasy Populations (Vol. 87, Iss. 1), Harilanto Razafindrazaka, Aurore Monnereau, Dina Razafindrazaka, Laure Tonasso, Stephanie Schiavinato, Jean-Aimé Rakotoarisoa, Chantal Radimilahy, Thierry Letellier, and Denis Pierron

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Hemochromatosis: Niche Construction and the Genetic Domino Effect in the European Neolithic (Vol. 87, Iss. 1), John M. McCullough, Kathleen M. Heath, and Alexis M. Smith

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Identification of Whole Mitochondrial Genomes from Venezuela and Implications on Regional Phylogenies in South America (Vol. 87, Iss. 1), Esther J. Lee and D. Andrew Merriwether

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Microdemographic Determinants of Population Recovery Among the Northern Ache (Vol. 87, Iss. 1), Jack D. Baker Jr, Kim Hill, A. Magdalena Hurtado, Adelamar Alcantara, Eddie Hunsinger, and Webb Sprague

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Mitochondrial DNA Suggests a Western Eurasian origin for Ancient (Proto-) Bulgarians (Vol. 87, Iss. 1), D V. Nesheva, S Karachanak-Yankova, M Lari, Y Yordanov, A Galabov, David Caramelli, and Draga Toncheva

Submissions from 2014

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How Much DNA is Lost? Measuring DNA Loss of STR Length Fragments Targeted by the PowerPlex 16® System Using the Qiagen MinElute Purification Kit (Vol. 86, Iss. 4), Brian M. Kemp, Misa Winters, Cara Monroe, and Jodi Lynn Barta

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Genetic analysis of 17 Y-STRs in a Mestizo population from the Central Valley of Mexico (Vol. 86, Iss. 4), Carla Santana, Gino Noris, Marco Antonio Meraz-Ríos, Jonathan J. Magaña, Emma S. Calderon-Aranda, Leonor C. Acosta-Saavedra, Maria de Lourdes Muñoz, and Rocio Gómez

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Estimation of Inbreeding and Substructure Levels in African-Derived Brazilian Quilombo Populations (Vol. 86, Iss. 4), Renan B. Lemes, Kelly Nunes, Diogo Meyer, Regina Célia Mingroni-Netto, and Paulo A. Otto

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Geographic Distribution And Adaptive Significance Of Genomic Structural Variants: An Anthropological Genetics Perspective (Vol. 86, Iss. 4), Muthukrishnan Eaaswarkhanth, Pavlos Pavlidis, and Omer Gokcumen

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A Mitochondrial Haplogroup is Associated with Decreased Longevity in a Historic New World Population (Vol. 86, Iss. 4), Loredana Castri, Donata Luiselli, Davide Pettener, Mauricio Melendez-Obando, Ramón Villegas-Palma, Ramiro Barrantes, and Lorena Madrigal

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Review of 'A Troublesome Inheritance' by Nicholas Wade (Vol. 86, Iss. 3), Laura R. Stein

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Troublesome Reflection: Racism as the Blind Spot in the Scientific Critique of Race (Vol. 86, Iss. 3), Charles C. Roseman

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Nicholas Wade and Race: Building a Scientific Façade (Vol. 86, Iss. 3), Jennifer Raff

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Review of 'A Troublesome Inheritance' by Nicholas Wade (Vol. 86, Iss. 3), Jonathan Marks

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A Troublesome Inheritance': Nicholas Wade’s Botched Interpretation of Human Genetics, History, and Evolution (Vol. 86, Iss. 3), Agustin Fuentes

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A homogenizing process of selection has maintained an 'ultra-slow' acetylation NAT2 variant in humans (Vol. 86, Iss. 3), Blandine Patillon, Pierre Luisi, Estella S. Poloni, Sotiria Boukouvala, Pierre Darlu, E. Genin, and Audrey Sabbagh

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HLA Class II Alleles in the Otomi population of the Mezquital Valley. A Genetic Approach to the History of Interethnic Migrations in the Mexican Central Plateau (Vol. 86, Iss. 3), Ana Itzel Juárez-Martín, Blanca Zoila González-Sobrino, Ángel Eduardo Camarena Olvera, and Ramcés Falfán-Valencia

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Population Genetic Structure of Traditional Populations in the Peruvian Central Andes and Implications for South American Population History (Vol. 86, Iss. 3), Graciela S. Cabana; Cecil M. Lewis, Jr.; Raúl Y. Tito; R. Alan Covey; Angela M. Cáceres; C. Leslie Castillo Pampas; Augusto F. De La Cruz; Diana Durand; Genevieve Housman; Brannon I. Hulsey; Gian Carlo Iannacone; Paul W. Lopez; Rolando Martínez; Ángel Medina; Olimpio Ortega Dávila; Karla Paloma Osorio Pinto; Susan I. Polo Santillán; Percy Rojas Domínguez; Meagan Rubel; Heather F. Smith; Silvia E. Smith; Verónica Rubín de Celis; Beatriz Lizárraga; and Anne C. Stone

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Human Diversity In Jordan: Polymorphic Alu Insertions In General Jordanian And Bedouin Groups (Vol. 86, Iss. 2), Daniela Zanetti, May Sadiq, Robert Carreras-Torres, Omar Khabour, Almuthanna Alkaraki, Esther Esteban, Marc Via, and Pedro Moral

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Human Paternal Lineages, Languages and Environment in the Caucasus (Vol. 86, Iss. 2), David Tarkhnishvili, Alexander Gavashelishvili, Marine Murtskhvaladze, Mariam Gabelaia, and Gigi Tevzadze

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Phylogeography of E1b1b1b-M81 Haplogroup and Analysis of its Subclades in Morocco (Vol. 86, Iss. 2), Ahmed Reguig, Nourdin Harich, Abdelhamid Barakat, and Hassan Rouba

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Mitochondrial DNA variability among six South-American Amerindian villages from the Pano linguistic group (Vol. 86, Iss. 2), Celso T. Mendes-Junior and Aguinaldo L. Simoes

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Questioning the “melting pot”: Analysis of Alu inserts in three population samples from Uruguay (Vol. 86, Iss. 2), Pedro C. Hidalgo, Patricia Mut, Elizabeth Ackermann, Gonzalo Figueiro, and Monica Sans

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Did Pre-Clovis People Inhabit the Paisley Caves (And Why Does It Matter)? (Vol. 86, Iss. 1), Stuart J. Fiedel

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Pedigree Structure and Kinship Measurements of a Mid-Michigan Community: A New North American Population Isolate Identified (Vol. 86, Iss. 1), Joseph D. Bonner, Rachel Fisher, James Klein, Qing Lu, Ellen Wilch, Karen H. Friderici, Jill L. Elfenbein, Debra L. Schutte, and Brian C. Schutte

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Comparing Partial Least Square Approaches in Gene-or Region-based Association Study for Multiple Quantitative Phenotypes (Vol. 86, Iss. 1), Zhongshang Yuan, Xiaoshuai Zhang, Fangyu Li, Jinghua Zhao, and Fuzhong Xue

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Effect of Recent Historical Events on Migration and Isonymic Stratification among the Rama Amerindians from Nicaragua (Vol. 86, Iss. 1), Norberto F. Baldi

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Celiac Disease as a Model for the Evolution of Multifactorial Disease in Humans (Vol. 86, Iss. 1), Aaron Sams and John Hawks

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Lactase Persistence Variants in Arabia and in the African Arabs (Vol. 86, Iss. 1), Edita Priehodova, Abdelhay Abdelsawy, Evelyne Heyer, and Viktor Cerny

Submissions from 2013

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No Evidence from Genome-Wide Data of a Khazar Origin for the Ashkenazi Jews (Vol. 85, Iss. 6), Doron M. Behar, Mait Metspalu, Yael Baran, Naama M. Kopelman, Bayazit Yunusbayev, Ariella Gladstein, Shay Tzur, Havhannes Sahakyan, Ardeshir Bahmanimehr, Levon Yepiskoposyan, Kristiina Tambets, Elza K. Khusnutdinova, Aljona Kusniarevich, Oleg Balanovsky, Elena Balanovsky, Lejla Kovacevic, Damir Marjanovic, Evelin Mihailov, Anastasia Kouvatsi, Costas Traintaphyllidis, Roy J. King, Ornella Semino, Antonio Torroni, Michael F. Hammer, Ene Metspalu, Karl Skorecki, Saharon Rosset, Eran Halperin, Richard Villems, and Noah A. Rosenberg

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Genetics and the Archaeology of Ancient Israel (Vol. 85, Iss. 6), Aaron J. Brody and Roy J. King

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Jewish genetic origins in the context of past historical and anthropological inquiries (Vol. 85, Iss. 6), John M. Efron

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Genetics and the history of the Samaritans: Y-chromosomal microsatellites and genetic affinity between Samaritans and Cohanim (Vol. 85, Iss. 6), Peter J. Oefner, Georg Hõlzl, Peidong Shen, Isaac Shpirer, Dov Gefel, Tal Lavi, Eilon Wolf, Jonathan Cohen, Cengiz Cinnioglu, Peter A. Underhill, Noah A. Rosenberg, Jochen Hochrein, Julie M. Granka, Jossi Hillel, and Marcus W. Feldman

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From Generation to Generation: The Genetics of Jewish Populations (Vol. 85, Iss. 6), Noah A. Rosenberg and Steven P. Weitzman

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Ancestry Informative Markers Clarify The Regional Admixture Variation In The Costa Rican Population (Vol. 85, Iss. 5), Rebeca Campos-Sánchez, Henriette Raventós, and Ramiro Barrantes

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Feeling the heat? Substantial variation in temperatures does not affect the proportion of males born in Australia (Vol. 85, Iss. 5), Barnaby J. Dixson, John Haywood, Philip J. Lester, and Diane K. Ormsby

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Intermittence for Humans spreading 45,000 years ago: from Eurasia to the Americas (Vol. 85, Iss. 5), J. C. Flores

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Genetic variation of X-STRs in the Wichí population from Chaco province, Argentina (Vol. 85, Iss. 5), Laura Angela Glesmann, Pablo Francisco Martina, and Cecilia Inés Catanesi

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How Studies Of Human Sex Ratios At Birth May Lead To The Understanding Of Several Forms Of Pathology (Vol. 85, Iss. 5), William H. James

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Analysis of uniparental lineages in two villages of Santiago del Estero, Argentina, seat of “Pueblos de Indios” in colonial times (Vol. 85, Iss. 5), Maia Pauro, Angelina García, Rodrigo Nores, and Darío A. Demarchi

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The -9/+9 polymorphism of the bradykinin receptor beta 2 gene and athlete status: A study involving two European cohorts. (Vol. 85, Iss. 5), Marek Sawczuk, Yevgeniya I. Timshina, Irina V. Astratenkova, Agnieszka Maciejewska-Karłowska, Agata Leońska-Duniec, Krzysztof Ficek, Leysan J. Mustafina, Paweł Cięszczyk, Tomasz Klocek, and Ildus I. Ahmetov

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Comparative morphology of the hominin and African ape hyoid bone, a possible marker of the evolution of speech (Vol. 85, Iss. 5), James Steele, Margaret Clegg, and Sandra Martelli

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Exploring the Relative Importance of Spatial and Environmental Variation on the Craniometrics of the Modern Portuguese (Vol. 85, Iss. 5), Katherine E. Weisensee

Submissions from 2012

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A Tale of Two Haplotypes: The EDA2R/AR Intergenic Region is the most Divergent Genomic Segment between Africans and East Asians in the Human Genome (Vol. 84, Iss. 6), Amanda M. Casto, Brenna M. Henn, Jeffery M. Kidd, Carlos D. Bustamante, and Marcus W. Feldman

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Front Speed of Language Replacement (Vol. 84, Iss. 6), Joaquim Fort and Joaquim Pérez-Losada

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The Effect of ACP1-ADA1 Genetic Interaction on Human Life Span (Vol. 84, Iss. 6), Nazzareno Lucarini, Valerio Napolioni, Andrea Magrini, and Fulvia Gloria

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Analysis of a Genetic Isolate: The Case of Carloforte (Italy) (Vol. 84, Iss. 6), R. Robledo, L. Corrias, V. Bachis, N. Puddu, A. Mameli, G. Vona, and C. M. Calò

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Extensive Population Structure in San, Khoe and Mixed Ancestry Populations from Southern Africa Revealed by 44 Short 5-SNP Haplotypes (Vol. 84, Iss. 6), Carina M. Schlebusch and Himla Soodyall

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Using the Neandertal and Denisova Genetic Data to Understand the Common MAPT 17q21 Inversion in Modern Humans (Vol. 84, Iss. 6), Núria Setó-Salvia, Federico Sánchez-Quinto, Eudald Carbonell, Carlos Lorenzo, David Comas, and Jordi Clarimón

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Genetic Susceptibility To Type 2 Diabetes: A Global Meta-Analysis Studying the Genetic Differences In Tunisian Populations (Vol. 84, Iss. 4), Rym Berhouma, S. Kouidhi, M. Ammar, H. Abid, T. Baroudi, H. Ennafaa, and A. Benammar-Elgaaied

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Paternal Lineage Analysis Supports An Armenian Rather Than A Central Asian Genetic Origin Of The Hamshenis (Vol. 84, Iss. 4), Ashot Margaryan, Ashot Harutyunyan, Zaruhi Khachatryan, Armine Khudoyan, and Levon Yepiskoposyan

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Genetic Characteristics Of An Ancient Nomadic Group In Northern China (Vol. 84, Iss. 4), Haijing Wang, Lu Chen, Binwen Ge, Ye Zhang, Hong Zhu, and Hui Zhou

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Human pelvis and long bones reveal differential preservation of ancient population history and migration out of Africa (Vol. 84, Iss. 2), Lia Betti, Noreen Von Cramon-Taubadel, and Stephen J. Lycett