30-Day Mortality and Cardiopulmonary Complication Rates in Patients Undergoing Emergency Surgery with Perioperative SARS-CoV-2 Infection
Research Mentor Name
Firas Abdollah MD
Research Mentor Email Address
Institution / Department
Department of Urology Henry Ford
Level of Research
INTRODUCTION AND OBJECTIVE: Continued vigilance of operative outcomes in COVID-19 patients is important given the relative novelty of the SARS-CoV-2 infection. We sought to evaluate the 30-day mortality and cardiopulmonary complication rates in patients undergoing emergency surgery with perioperative COVID-19, in comparison to a control group of medically managed COVID-19 patients that did not require a surgical intervention.
METHODS: A retrospective chart review at a single tertiary-care hospital in Michigan was undertaken. Patients who had tested positive for SARS-CoV-2 infection either 7 days before or within 30 days after surgery during March-May 2020 were included in the study (n=52). Propensity score matched (1:6) patients who had been positive for SARS CoV-2 infection during this time-period but did not undergo surgery served as controls (n=314). The primary endpoint was 30-day mortality. Secondary endpoints included cardiac and pulmonary complications. Multivariable logistic regression analyses were utilized to account for baseline differences.
RESULTS: The 30-day mortality (17.3% vs 13.1%, p=0.408) and cardiac (28.9% vs 19.1%, p=0.107) and pulmonary complication (55.8% vs 49.4%, p=0.392) rates were similar in the surgical and the non-surgical groups. Multivariable analyses confirmed that emergency surgical intervention was not associated with increased odds for any of the studied adverse events (p>0.10 for all 3 endpoints).
CONCLUSIONS: Our analysis of 366 novel coronavirus patients demonstrates that patients undergoing emergency surgery with SARS-CoV-2 infection do not have an increased risk for 30-day mortality and cardiopulmonary complications compared to their counterparts that do not require surgery. The importance of this study is that an emergency intervention does not portend a poorer prognosis among patients with a confirmed SARS-CoV-2 Infection.
Medicine and Health Sciences
Sood MD, Akshay; Corsi, Nicholas; Butaney MD, Mohit; Keeley MS, Jacob; Bronkema, Chandler; Affas MD, Ziad; Farah, Guillaume; Chien, Michael; Hanna, Renee; Wertheimer, Stephen; Chang MD, Steven; Rambhatla MD, Amarnath; Stricker MD, Hans; Peabody MD, James; Menon MD, Mani; Rogers MD, Craig; Rakic, Nikola; and Abdollah MD, Firas, "30-Day Mortality and Cardiopulmonary Complication Rates in Patients Undergoing Emergency Surgery with Perioperative SARS-CoV-2 Infection" (2021). Medical Student Research Symposium. 91.
This project was supported by funding from the 2020 Wayne State Medical Student Research Fellowship.