30-Day Mortality and Cardiopulmonary Complication Rates in Patients Undergoing Emergency Surgery with Perioperative SARS-CoV-2 Infection

Authors

Akshay Sood MD, Henry Ford Health System
Nicholas Corsi, Wayne State UniversityFollow
Mohit Butaney MD, Mayo Clinic
Jacob Keeley MS, Henry Ford Health System
Chandler Bronkema, Wayne State University
Ziad Affas MD
Guillaume Farah, Wayne State University
Michael Chien, Wayne State University
Renee Hanna, Michigan State University
Stephen Wertheimer, Wayne State University
Steven Chang MD, Henry Ford Health System
Amarnath Rambhatla MD, Henry Ford Health System
Hans Stricker MD, Henry Ford Health System
James Peabody MD, Henry Ford Health System
Mani Menon MD, Henry Ford Health System
Craig Rogers MD, Henry Ford Health System
Nikola Rakic, Henry Ford Health System
Firas Abdollah MD, Henry Ford Health System

Research Mentor Name

Firas Abdollah MD

Research Mentor Email Address

fabdoll1@hfhs.org

Institution / Department

Department of Urology Henry Ford

Document Type

Research Abstract

Research Type

clinicalresearch

Level of Research

no

Abstract

INTRODUCTION AND OBJECTIVE: Continued vigilance of operative outcomes in COVID-19 patients is important given the relative novelty of the SARS-CoV-2 infection. We sought to evaluate the 30-day mortality and cardiopulmonary complication rates in patients undergoing emergency surgery with perioperative COVID-19, in comparison to a control group of medically managed COVID-19 patients that did not require a surgical intervention.

METHODS: A retrospective chart review at a single tertiary-care hospital in Michigan was undertaken. Patients who had tested positive for SARS-CoV-2 infection either 7 days before or within 30 days after surgery during March-May 2020 were included in the study (n=52). Propensity score matched (1:6) patients who had been positive for SARS CoV-2 infection during this time-period but did not undergo surgery served as controls (n=314). The primary endpoint was 30-day mortality. Secondary endpoints included cardiac and pulmonary complications. Multivariable logistic regression analyses were utilized to account for baseline differences.

RESULTS: The 30-day mortality (17.3% vs 13.1%, p=0.408) and cardiac (28.9% vs 19.1%, p=0.107) and pulmonary complication (55.8% vs 49.4%, p=0.392) rates were similar in the surgical and the non-surgical groups. Multivariable analyses confirmed that emergency surgical intervention was not associated with increased odds for any of the studied adverse events (p>0.10 for all 3 endpoints).

CONCLUSIONS: Our analysis of 366 novel coronavirus patients demonstrates that patients undergoing emergency surgery with SARS-CoV-2 infection do not have an increased risk for 30-day mortality and cardiopulmonary complications compared to their counterparts that do not require surgery. The importance of this study is that an emergency intervention does not portend a poorer prognosis among patients with a confirmed SARS-CoV-2 Infection.

Disciplines

Medicine and Health Sciences

Recommended Citation

Sood MD, Akshay; Corsi, Nicholas; Butaney MD, Mohit; Keeley MS, Jacob; Bronkema, Chandler; Affas MD, Ziad; Farah, Guillaume; Chien, Michael; Hanna, Renee; Wertheimer, Stephen; Chang MD, Steven; Rambhatla MD, Amarnath; Stricker MD, Hans; Peabody MD, James; Menon MD, Mani; Rogers MD, Craig; Rakic, Nikola; and Abdollah MD, Firas, "30-Day Mortality and Cardiopulmonary Complication Rates in Patients Undergoing Emergency Surgery with Perioperative SARS-CoV-2 Infection" (2021). Medical Student Research Symposium. 91.
https://digitalcommons.wayne.edu/som_srs/91

Comments

This project was supported by funding from the 2020 Wayne State Medical Student Research Fellowship.