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Theses/Dissertations from 2022

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Mitochondrial Morphosis Events During Myocardial Ischemia- Reperfusion: Are Opa1 And Cristae Integrity At The Heart Of The Matter?, Andrew Russell Kulek

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Investigating The Metal Binding And Transport Properties Of Znta And Zupt, Cameron Sevon Roberts

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How The Structural Uniqueness Makes Smyd Proteins So Special, Yingxue Zhang

Theses/Dissertations from 2019

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Biochemical, Structural, And Drug Design Studies Of Aspartate Transcarbamoylase From Pseudomonas Aeruginosa And Staphylococcus Aureus, Chandni Patel

Theses/Dissertations from 2018

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Methionine Sulfoximine: A Novel Anti Inflammatory Agent, Tyler Peters

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Alternative Strategies To Inhibit Lysine Methyltransferases And Deubiquitinases In Human Cancers, Nicholas Spellmon

Theses/Dissertations from 2017

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Effect Of Endoplasmic Reticulum Stress On Vascular Smooth Muscle Cells And Its Regulation Of Sm22α, Neeraja Priyanka Annam

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P120 Catenin Regulates Inflammation In Macrophage, Xiaoqing Guan

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Structural Basis Of Membrane Protein Scaffolding And Signaling In Human Disease, Joshua Holcomb

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Biochemical, Structural, And Drug Design Studies Of Norovirus And Zika Virus Proteases, Ben Kuiper

Theses/Dissertations from 2016

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Characterization Of The Yeast Cysteine Desulfurase Complex Within The Mitochondrial Fe-S Cluster Biogenesis, Dulmini Pabasara Barupala

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Investigation Of Mutations In Nuclear Genes That Affect The Atp Synthase, Russell Dsouza

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Insights Into De Novo Fes-Cluster Biogenesis Via The Eukaryotic Fes-Cluster (isc) Pathway In Vitro, Stephen Paul Dzul

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A Critical Role Of Cxcr2 Pdz Motif-Mediated Interactions In Endothelial Progenitor Cell Homing And Angiogenesis, Yuning Hou

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Regulation Of Cytochrome C Functions By Phosphorylation, Gargi Mahapatra

Theses/Dissertations from 2014

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Structural Basis Of Epigenetic Regulation And Protein Scaffolding In Development And Diseases, Yuanyuan Jiang

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Characterization Of Initial Iron Binding Location And The Structure/iron Binding Site On S.cerevisiae Isu And On D.melanogaster Frataxin, Andria V. Rodrigues

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Cxcr2 Macromolecular Complex In Pancreatic Cancer: A Potential Therapeutic Target In Tumor Growth, Shuo Wang

Theses/Dissertations from 2013

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Biochemical, Structural, And Drug Design Studies Of Multi-Drug Resistant Hiv-1 Therapeutic Targets, Tamaria Grace Dewdney

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Elucidation Of The Functional Role Of Pcbp-The Cytosolic Iron Chaperone Protein Family, In Cellular Iron Homeostasis, Poorna Subramanian

Theses/Dissertations from 2012

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Understanding the gender-based mechanism of mso in als mice: a metabolic characterization of the sod1-g93a mouse model, Monica Ann Bame

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The role of cad,flash and fam129b in cancer cell survial and apoptosis, Song Chen

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Use of methionine sulfoximine to dissect the role of glutamine synthetase and glutamine in progression of acute liver failure, Amruta Anil Jambekar

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Development of an in-cell förster resonance energy transfer technique to study protein structure inside living cells, Victoria Lynn Murray

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Drug resistance mechanisms and drug design strategies for human immunodeficiency virus and hepatitis c virus proteases, Yong Wang

Theses/Dissertations from 2011

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A novel in vivo protein refolding technique, Yuefei Huang

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Crystallographic, Molecular Dynamics, And Enzymatic Studies Of Multi-Drug Resistant Hiv-1 Protease And Implications For Structure Based Drug Design (project 1); Crystallographic Studies Of Human Myelin Protein Zero (project 2), Zhigang Liu

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Molecular Details Of The Mitochondrial Iron Sulfur Cluster Assembly Pathway, Swati Rawat

Theses/Dissertations from 2010

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Application Of Magnetic Resonance Imaging To Understanding The Pathogenesis Of The X-Linked Leukodystrophy Pelizaeus-Merzbacher Disease, Jeremy Jerome Laukka

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Investigating The Metal Binding Sites In Znta, A Zinc Transporting Atpase, Sandhya Muralidharan

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Characterization Of Arsd: An Arsenic Chaperone For The Arsab As(iii)-Translocating Atpase, Jianbo Yang

Theses/Dissertations from 2003

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Biochemical and functional studies on CopA: The Escherichia Coli Copper Ion Translocating P-Type ATPase., Bin. Fan

Theses/Dissertations from 2001

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Phenylbutyrate targets in yeast, Andrew Marion Grzanowski

Theses/Dissertations from 2000

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Subdomain organization and function in the carbamoyl phosphate synthetase of E. coli and mammalian CAD, Anne Bouvier

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Examination of the effects of two mutations in the ampC structural gene of enterobacter cloacae P99, Ruben Gomez

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Mechanistic studies of (S)-mandelate dehydrogenase from Pseudomonas putida, a flavin-dependent alpha-hydroxy acid dehydrogenase, Isabelle E. Lehoux

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Structure of connective tissue activating peptide-III complex with polyvinylsulfonic acid and structure comparison of two platelet factor 4 mutants with the wild-type, Jian. Yang

Theses/Dissertations from 1999

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Mechanism of glutamine hydrolysis and interdomain communication by mammalian carbamoyl phosphate synthetase, Anura. Hewagama

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The role of linker subunits in the reassembly of hexagonal bilayer structure of Lumbricus hemoglobin, Askar R. Kuchumov

Theses/Dissertations from 1998

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Structural and functional characterization of the ARSA ATPASE, the catalytic subunit of the arsenic resistance pump, Jiaxin. Li

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Characterization of the regulatory domain of the mammalian multifunctional De Novo pyrimidne biosynthetic enzyme CAD, Nisha Sahay