Research Mentor Name

Dr. Jeffrey Johnson, MD

Research Mentor Email Address

jjohns52@hfhs.org

Institution / Department

Henry Ford Health

Document Type

Research Abstract

Research Type

clinicalresearch

Level of Research

no

Abstract

Background

Some patients with symptomatic gallstones present with more severe disease, have more difficult anatomy and require more complex operations. While cholecystitis has a female preponderance, some observe a trend towards more challenging disease in male patients. The confluence of gender and patient acuity has not been thoroughly investigated. We hypothesize that males present with worse disease compared to females.

Methods

The analysis cohort of adults who underwent cholecystectomies was filtered from a five-hospital health system administration registry containing inpatients admitted from Fall 2015 to Fall 2021. The dataset contained demographics, health characteristics, and variables reflecting disease severity and acuity. Univariate analysis and multivariate logistic regression were performed to highlight the relationship between patient variables, including gender, and disease acuity. The data were de-identified prior to analysis and deemed exempt from IRB review. Data were analyzed using R within R-Studio.

Results

Of 2789 cholecystectomy patients, 1616 (58%) were female and 1173 (42%) were male. Univariate analysis highlighted that males had higher rates of harm (p-value: 0.002), longer inpatient length of stay (p-value:

Conclusion

Males present with worse risk-adjusted gallstone disease and require more hospital resources.

Disciplines

Digestive System Diseases | Educational Assessment, Evaluation, and Research | Medicine and Health Sciences

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