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Research Mentor Name

Dr. Vijaya Arun Kumar

Research Mentor Email Address

vkumar@med.wayne.edu

Institution / Department

Wayne State University School of Medicine

Document Type

Research Abstract

Research Type

clinicalresearch

Level of Research

no

Abstract

Catheter Directed Thrombolysis (CDT) or Systemic Thrombolysis (ST) are current standards of care for patients experiencing a Massive (MPE) or Submassive (SPE) Pulmonary Embolism which are categories that are defined by AHA guidelines for the Emergency Department. The Pulmonary Embolism Severity Index (PESI), a five-tier system, is a composite metric that can risk stratify PE into low risk (tiers 1,2) for SPE and high risk (tiers 3,4,5) for MPE, predicting mortality and outcomes. This study aims to determine if CDT or ST/no intervention (ST/NI) has better outcomes for MPE and SPE patients, while using PESI as a risk stratification tool. We conducted a retrospective analysis of patients from 2010 – 2016 who underwent CDT or ST/NI, matching patients using ten variables to yield N= 336: with equal proportions receiving CDT and ST/NI. 96 patients were in the low risk PESI group and 240 patients were in the high risk PESI group. In both low and high risk PESI groups, CDT intervention was associated with longer length of stay, (p

Disciplines

Analytical, Diagnostic and Therapeutic Techniques and Equipment | Medicine and Health Sciences

Comments

The authors would like to thank Dr. Mahir Elder M.D. for providing the data for the patients that underwent CDT treatment. We would also like to thank the Wayne State University School of Medicine Medical Student Research Fellowship program for providing a stipend while this research was being conducted. There are no other financial disclosures.

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