Mai T. Lam
Adipose-derived Stem Cells (ASC’s) provide an optimal source for potentially graft replacing, tissue-engineered vessel constructs due to their ease of extraction and ability to be patient-specific. In order to make ASC ring constructs a more viable replacement for grafts, they need to have mechanical properties similar to native arteries, which is largely influenced by the extracellular matrix protein collagen. TGFβ-1 is known to stimulate collagen production in ASC’s, so this study explores the effect that TGFβ-1 has on the resulting thickness and tensile strength of ASC ring constructs.
Biomaterials | Molecular, Cellular, and Tissue Engineering
Apil, Ashley C., "The Effect of TGFβ-1 on Adipose-derived Stem Cell (ASC) Ring Constructs" (2017). ROEU 2016-17. 6.