We investigated the distribution of haptoglobin (HP) alleles and haplotypes among Africans (Ghanaians), Europeans (from South Africa), and Chinese. HP*1F was present only in Africans and Europeans, whereas HP*del was unique to Chinese. Six base substitutions at the promoter region were population specific. Only 3 out of 18 haplotypes were shared among the populations. A probable application of HP in human population genetics appears legitimate.
Teye, Kwesi; Soejima, Mikiko; Quaye, Isaac K. E.; and Pang, Hao
"Haptoglobin Gene Promoter Polymorphism and Haplotypes Are Unique in Different Populations,"
1, Article 10.
Available at: https://digitalcommons.wayne.edu/humbiol/vol78/iss1/10