Beta 1 Adrenergic Receptor Polymorphisms Arg389Gly and Ser49Gly in the Amerindian and Mestizo Populations of Mexico

Document Type

Article

Authors

Jose Manuel Fragoso, Instituto Nacional de Cardiología Ignacio ChávezFollow
Jose Manuel Rodriguez-Perez, Instituto Nacional de Cardiología Ignacio Chávez
Nadia Perez-Vielma, Instituto Nacional de Cardiología Ignacio Chávez
Nancy Martinez-Rodriguez, Instituto Nacional de Cardiología Ignacio Chávez

Abstract

The 1 adrenergic receptor genotypes (Ser49Gly and Arg389- Gly) were determined in 190 individuals from 3 Mexican populations. Mestizos and Teenek present the highest frequencies for the *Arg allele and the lowest frequencies for the *Gly allele (Arg389Gly) compared to European, Asian, and African populations. Mayos present the highest frequency for the *Gly allele. The knowledge of the distribution of these alleles could help define the significance of these polymorphisms as genetic susceptibility markers in Amerindian populations.

Recommended Citation

Fragoso, Jose Manuel; Rodriguez-Perez, Jose Manuel; Perez-Vielma, Nadia; and Martinez-Rodriguez, Nancy (2005) " Beta 1 Adrenergic Receptor Polymorphisms Arg389Gly and Ser49Gly in the Amerindian and Mestizo Populations of Mexico," Human Biology: Vol. 77: Iss. 4, Article 9.
Available at: https://digitalcommons.wayne.edu/humbiol/vol77/iss4/9