CFTR Haplotype Distribution in the Brazilian Western Amazonian Region

Document Type

Article

Authors

M I. O. Heckmann, Instituto de Pesquisa em Patologias Tropicais de RondôniaFollow
C T. Mendes-Junior, Universidade de Sao Paulo
M S. Tada, Instituto de Pesquisa em Patologias Tropicais de Rondônia
M G. Santos, Instituto de Pesquisa em Patologias Tropicais de Rondoˆnia

Abstract

Two hundred twenty-one individuals from four groups located around the Brazilian town of Porto Velho, Rondônia, were studied in relation to four sites located within or near the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The allele frequencies, when considered individually, do not depart markedly from frequencies obtained from other populations of mainly European descent. However, when haplotypes were estimated, two of the groups departed markedly from other Brazilian and non-Brazilian samples. This finding is probably related to the complex multiethnic origin of these groups.

Recommended Citation

Heckmann, M I. O.; Mendes-Junior, C T.; Tada, M S.; and Santos, M G. (2005) "CFTR Haplotype Distribution in the Brazilian Western Amazonian Region," Human Biology: Vol. 77: Iss. 4, Article 7.
Available at: https://digitalcommons.wayne.edu/humbiol/vol77/iss4/7