DAT1 VNTR Allele Frequencies in the Omani Population

Document Type

Article

Authors

M Simsek, Sultan Qaboos UniversityFollow
K Lawatia, Sultan Qaboos University
S Al-Adawi, Sultan Qaboos University
M Al-Sharbatt, Sultan Qaboos University

Abstract

To determine the genetic variability at the human DAT1 VNTR locus, we screened 110 healthy Omani blood donors using the polymerase chain reaction (PCR) and agarose gel electrophoresis. Two common alleles (DAT1*9 and DAT1*10) were observed with a frequency of 0.332 and 0.609, respectively. There were also five rare alleles (*3, *6, *7, *8, and *11). The frequency of the observed genotypes was not significantly different from the expected Hardy-Weinberg distribution. We compared the Omani DAT1 alleles with similar data from other populations.

Recommended Citation

Simsek, M; Lawatia, K; Al-Adawi, S; and Al-Sharbatt, M (2005) "DAT1 VNTR Allele Frequencies in the Omani Population," Human Biology: Vol. 77: Iss. 2, Article 10.
Available at: https://digitalcommons.wayne.edu/humbiol/vol77/iss2/10