Characteristic β-Globin Gene Cluster Haplotypes of Evenkis and Oroqens in North China

Document Type

Article

Authors

Koji Shimizu, Laboratory of Biology, Naruto University of Education, Tokushima 772-8502, Japan.
Azusa Marubayashi, Laboratory of Biology, Naruto University of Education, Tokushima 772-8502, Japan.
Kozue Tokimasa, Laboratory of Biology, Naruto University of Education, Tokushima 772-8502, Japan.
Shinji Harihara, Department of Biological Science (Anthropology), Graduate School of Science, University of Tokyo, Tokyo 113-0033, Japan.
Keiichi Omoto, Faculty of Letters, St. Andrew’s University, Osaka 594-1198, Japan.
Tadashi Imanishi, Biological Information Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo 135-0064, Japan.
Luping Hao, Laboratory for Human and Animal Genetic Studies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101; and China Institute of Genetics, China Academy of Sciences, Beijing, China.
Feng Jin, Laboratory for Human and Animal Genetic Studies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101; and China Institute of Genetics, China Academy of Sciences, Beijing, China.

Abstract

Haplotype frequencies of the β-globin gene cluster were estimated for 114 Evenkis and 81 Oroqens from northeast China, and their characteristics were compared with those in Japanese, Koreans, and three Colombian Amerindian groups of South America (Wayuu, Kamsa, and Inga tribes). A major 5 subhaplotype (5 to the δ-globin gene) was in Evenkis, whereas , , and were the major subhaplotypes in Oroqens. One possible candidate for an ancestral 5 subhaplotype, , was found in one Evenki (0.5%) and three Oroqen chromosomes (2.0%). They were observed as heterozygous forms for and . Major haplotypes were , , and in Evenkis, whereas they were , , , and in Oroqens. The lowest Nei’s genetic distance values of Evenkis or Oroqens based on the 5 subhaplotype frequency distributions were observed in relation to theWayuu or Koreans, respectively, but those of Evenkis and Oroqens based on the haplotype frequency distributions were found in relation to Koreans.

Recommended Citation

Shimizu, Koji; Marubayashi, Azusa; Tokimasa, Kozue; Harihara, Shinji; Omoto, Keiichi; Imanishi, Tadashi; Hao, Luping; and Jin, Feng (2004) "Characteristic β-Globin Gene Cluster Haplotypes of Evenkis and Oroqens in North China," Human Biology: Vol. 76: Iss. 5, Article 8.
Available at: https://digitalcommons.wayne.edu/humbiol/vol76/iss5/8