Distribution of CCR5- 32, CCR2-64I, and SDF1-3 A Mutations in Populations from the Brazilian Amazon Region

Document Type

Article

Authors

• Fernanda Andreza de Pinho Lott Carvalhaes, Laboratory of Human and Medical Genetics, Department of Pathology, Center for Biological Sciences, Federal University of Para´, 66075-900 Bele´m, Para´, Brazil.
• Greice Lemos Cardoso, Laboratory of Human and Medical Genetics, Department of Pathology, Center for Biological Sciences, Federal University of Para´, 66075-900 Bele´m, Para´, Brazil.
• Igor Guerreiro Hamoy, Laboratory of Human and Medical Genetics, Department of Pathology, Center for Biological Sciences, Federal University of Para´, 66075-900 Bele´m, Para´, Brazil.
• Yan Tat Liu, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DS, United Kingdom.
• João Farias Guerreiro, Laboratory of Human and Medical Genetics, Department of Pathology, Center for Biological Sciences, Federal University of Para´, 66075-900 Bele´m, Para´, Brazil.

Abstract

The frequency distribution of the CCR5- 32, CCR2-64I, and SDF1-3 A alleles was studied in the urban population of Bele´m and in Afro- Brazilians, Amerindians, and Japanese immigrants in the state of Para´, Brazil. The results suggest that Amerindians may be genetically more susceptible to HIV-1 infection and disease progression than the other human groups studied.

Recommended Citation

Carvalhaes, Fernanda Andreza de Pinho Lott; Cardoso, Greice Lemos; Hamoy, Igor Guerreiro; Liu, Yan Tat; and Guerreiro, João Farias (2004) "Distribution of CCR5- 32, CCR2-64I, and SDF1-3 A Mutations in Populations from the Brazilian Amazon Region," Human Biology: Vol. 76: Iss. 4, Article 11.
Available at: https://digitalcommons.wayne.edu/humbiol/vol76/iss4/11