Distribution of CCR5- 32, CCR2-64I, and SDF1-3 A Mutations in Populations from the Brazilian Amazon Region

Document Type

Article

Authors

Fernanda Andreza de Pinho Lott Carvalhaes, Laboratory of Human and Medical Genetics, Department of Pathology, Center for Biological Sciences, Federal University of Para´, 66075-900 Bele´m, Para´, Brazil.
Greice Lemos Cardoso, Laboratory of Human and Medical Genetics, Department of Pathology, Center for Biological Sciences, Federal University of Para´, 66075-900 Bele´m, Para´, Brazil.
Igor Guerreiro Hamoy, Laboratory of Human and Medical Genetics, Department of Pathology, Center for Biological Sciences, Federal University of Para´, 66075-900 Bele´m, Para´, Brazil.
Yan Tat Liu, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DS, United Kingdom.
João Farias Guerreiro, Laboratory of Human and Medical Genetics, Department of Pathology, Center for Biological Sciences, Federal University of Para´, 66075-900 Bele´m, Para´, Brazil.

Abstract

The frequency distribution of the CCR5- 32, CCR2-64I, and SDF1-3 A alleles was studied in the urban population of Bele´m and in Afro- Brazilians, Amerindians, and Japanese immigrants in the state of Para´, Brazil. The results suggest that Amerindians may be genetically more susceptible to HIV-1 infection and disease progression than the other human groups studied.

Recommended Citation

Carvalhaes, Fernanda Andreza de Pinho Lott; Cardoso, Greice Lemos; Hamoy, Igor Guerreiro; Liu, Yan Tat; and Guerreiro, João Farias (2004) "Distribution of CCR5- 32, CCR2-64I, and SDF1-3 A Mutations in Populations from the Brazilian Amazon Region," Human Biology: Vol. 76: Iss. 4, Article 11.
Available at: https://digitalcommons.wayne.edu/humbiol/vol76/iss4/11