STR Polymorphisms in the Population of the Island of Hvar

Document Type

Article

Authors

Irena Martinović, Institute for Antropological Research
Lovorka Barać, Institute for Anthropological Research
Ivana Furač, University Medical School
Branka Janićijević, Institute for Anthropological Research
Milovan Kubat, University Medical School
Marijana Peričić, Institute for Anthropological Research
Božidarka Vidović, University Medical School
Pavao Rudan, Institute for Anthropological Research

Abstract

The aim of this study is to analyze short tandem repeat (STR) variation using data on 9 loci (D3S1358, VWA, FGA, THOl, TPOX, CSF1PO, D5S818, D13S317, D7S820) from the subpopulations of 6 villages on the island of Hvar, Croatia. The STR data help us to analyze the genetic structure of Hvar. The analysis of STR data in this study indicated genetic homogeneity among the village subpopulations on Hvar and the lack of the so-called east-west dichotomy, which had been indicated by some previous multidisciplinary anthropological studies. The observed value of GST (0.030) is most probably a consequence of high STR mutation rates, which produce a high level of within-group (village) diversity relative to total diversity of the population. The validity of STR markers in assessing genetic structure of small populations and especially in determining the relationships among closely related and reproductively isolated groups remains to be further evaluated.

Recommended Citation

Martinović, Irena; Barać, Lovorka; Furač, Ivana; Janićijević, Branka; Kubat, Milovan; Peričić, Marijana; Vidović, Božidarka; and Rudan, Pavao (1999) "STR Polymorphisms in the Population of the Island of Hvar," Human Biology: Vol. 71: Iss. 3, Article 3.
Available at: https://digitalcommons.wayne.edu/humbiol/vol71/iss3/3