Incidence of Cystic Fibrosis in Saguenay-Lac-Si.-Jean (Quebec, Canada)

Document Type

Article

Authors

Jocelyne Daigneault, Universite du Quebec a Chicoutimi
Gervais Aubin, Hopital de Chicoutimi
Fernand Simard, Hopital de Chicoutimi
Marc de Braekeleer, Universite du Quebec a Chicoutimi

Abstract

The incidence of cystic fibrosis (CF) in Saguenay-Lac- St.-Jean, a geographically isolated region of Quebec, was estimated to be 1 in 902 during the period 1975-1988. The carrier rate was calculated to be 1 in 15 inhabitants. The high incidence of CF in Saguenay-Lac-St.-Jean is probably the result of a founder effect and genetic drift for one or more mutations. Historical, demographic, and social factors also may have contributed to the high incidence.

Recommended Citation

Daigneault, Jocelyne; Aubin, Gervais; Simard, Fernand; and Braekeleer, Marc de (1992) "Incidence of Cystic Fibrosis in Saguenay-Lac-Si.-Jean (Quebec, Canada)," Human Biology: Vol. 64: Iss. 1, Article 11.
Available at: https://digitalcommons.wayne.edu/humbiol/vol64/iss1/11