Factor VIII:C, ABO Blood Groups, and Black Admixture in a Brazilian Sample

Document Type

Article

Authors

A. M.V.M.D. Lima, Universidade Federal da Bahia, Brazil
E. S. Azevêdo, Universidade Federal da Bahia, Brazil

Abstract

The effects of ABO blood groups and black admixture on the level of factor VIII:C are studied in healthy adults from Salvador, Bahia, Brazil. A racially mixed sample of 125 males was selected as follows: 25 whites, 25 light mulattoes, 25 medium mulattoes, 25 dark mulattoes, and 25 blacks. Levels of both factor VIII:C and KPTT followed normal distributions. O blood group subjects showed lower factor VIII:C levels (110.20 ± 30.76%) than non-0 blood group members (135.24 ± 31.42%) (* 123 = 4.47; p < 0.0001) and higher KPTT levels (37.69 ± 4.57 s) than non-O blood group subjects (35.25 ± 3.82 s) (*123 = 3.24; p < 0.01). By holding ABO blood type constant, there is a significant racial effect (white) on lowering the factor VIII:C level within both blood group O (*43 = 2.23; p < 0.05) and non-O (*36 = 3.44; p < 0.002). There is no interaction effect of race and blood group (F = 0.19; p > 0.6) on the factor VIII:C levels.

Recommended Citation

Lima, A. M.V.M.D. and Azevêdo, E. S. (1991) "Factor VIII:C, ABO Blood Groups, and Black Admixture in a Brazilian Sample," Human Biology: Vol. 63: Iss. 1, Article 7.
Available at: https://digitalcommons.wayne.edu/humbiol/vol63/iss1/7