Electrophoretic and Isoelectric Focusing Studies in Brazilian Indians: Data on Four Systems

Document Type

Article

Authors

A. L. Simōes, Departamento de Genética, Faculdade de Medicina, Campus Universitário, SP, Brazil
J. Kömpf, Institut für Anthropologie und Humangenetik der Universität Tübingen, Tübingen, Federal Republic of Germany
H. Ritter, Institut für Anthropologie und Humangenetik der Universität Tübingen, Tübingen, Federal Republic of Germany
C. Luckenbach, Institut für Anthropologie und Humangenetik der Universität Tübingen, Tübingen, Federal Republic of Germany
H. Zischler, Institut für Anthropologie und Humangenetik der Universität Tübingen, Tübingen, Federal Republic of Germany
F. M. Salzano, Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

Abstract

Three-hundred ninety-nine individuals living in seven populations of two Brazilian Indian tribes (Macushi and Igana River Indians) were tested for the phosphoglucomutase 1 (PGM 1), properdin factor B (BF), haptoglobin (HP), and α-1-antitrypsin (PI) systems. We observed significant internal heterogeneity in the two tribes for the PGM 1 alleles and in the Macushi for the HP markers. Frequencies in three of the four systems (the exception being BF) also show clear differences in the Macushi and Igana River Indians. Compared with other ethnic groups, South American Indians generally present high frequencies of PGM1*1B, BF*S, HP*1S, and PI*M3. On the other hand, PGM1*1A, PI*M1, and PI*M2 are reduced, and HP*1F is absent or rare. This is the first report about HP subtypes among American Indians.

Recommended Citation

Simōes, A. L.; Kömpf, J.; Ritter, H.; Luckenbach, C.; Zischler, H.; and Salzano, F. M. (1989) "Electrophoretic and Isoelectric Focusing Studies in Brazilian Indians: Data on Four Systems," Human Biology: Vol. 61: Iss. 3, Article 9.
Available at: https://digitalcommons.wayne.edu/humbiol/vol61/iss3/9