Seasonal Effect on the Variability of Summer Immunoglobulin Levels

Document Type

Article

Authors

Gordon L. Nordby, The University of Michigan Medical School, Ann Arbor, Michigan
James T. Cassidy, The University of Michigan Medical School, Ann Arbor, Michigan

Abstract

Variability of the three major classes of immunoglobulins (IgA, IgG, and IgM) relative to sex and age must be considered to interpret accurately their serum concentrations. In the present study, analyses of seasonal changes in the mean and variance of immunoglobulin levels are reported for 3,210 unselected individuals from 5 to 94 years of age. Significant variation in mean immunoglobulin concentrations based upon date was not found. However, an important seasonal variability in the range of the serum levels was demonstrated.

Recommended Citation

Nordby, Gordon L. and Cassidy, James T. (1983) "Seasonal Effect on the Variability of Summer Immunoglobulin Levels," Human Biology: Vol. 55: Iss. 4, Article 8.
Available at: https://digitalcommons.wayne.edu/humbiol/vol55/iss4/8