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Rates of adrenaline and noradrenaline urinary excretion over three periods on both a work day and a rest day have been determined among 464 adult women in the Otmoor villages of Oxfordshire. Various associations between these rates and different aspects of lifestyle and subjective sense of well being, as ascertained by questionnaire, are detectable, particularly on the morning of the rest day. At this time frustration and general dissatisfaction with life; high coffee and low tea consumption; and cigarette smoking are associated with high adrenaline outputs, and together account for 7.2% of the observed adrenaline variance. The independent contributions to noradrenaline variance are less clear, but a lifestyle factor embrac­ing the taking of sleep tablets and organization of daily tasks significantly contributes to this variance.