Placental Alkaline Phosphatase in a Sudanese Population: Polymorphism and Enzyme Activity

Document Type

Article

Authors

N Saha, University of Khartoum, Khartoum, Sudan
K A. Gumaa, Kuwait University, Kuwait
A P.W Samuel, University of Khartoum, Khartoum, Sudan
H El-Naeim, University of Khartoum, Khartoum, Sudan

Abstract

Placental alkaline phosphatase phenotypes and activity were determined in 229 placentae obtained from Sudanese mothers. The estimated gene frequencies of the common alleles PlSl, Pli1 and Plfl were 0.7367, 0.1615 and 0.1018 respectively. There was a significant deviation from Hardy-Weinberg equilibrium with an excess of homozygous phenotypes, probably due to the high degree of inbreeding in the population. The enzymatic activity was 22.0 ± 12.5 to 26.4 ± 10.8 U/g placenta with no significant difference according to phenotypes.

Recommended Citation

Saha, N; Gumaa, K A.; Samuel, A P.W; and El-Naeim, H (1979) "Placental Alkaline Phosphatase in a Sudanese Population: Polymorphism and Enzyme Activity," Human Biology: Vol. 51: Iss. 3, Article 8.
Available at: https://digitalcommons.wayne.edu/humbiol/vol51/iss3/8