Serum Protein and Isoenzyme Polymorphisms from Nottingham, England

Document Type

Article

Authors

R A. Cartwright, University of Durham, Durham City, England
H J. Hargreaves, University of Durham, Durham City, England
E Sunderland, University of Durham, Durham City, England

Abstract

Data relating to five independent genetic polymorphisms are presented.The material is drawn from the English Midlands and consists of nearly 1,000 people typed for red blood cell acid phosphatase, adenylate kinase and esterase D isoenzymes together with the serum proteins, haptoglobin and transferrin. The data show some regional differences which are difficult to interpret partly due to the lack of British comparative material. Further investigation of the material shows that some, if not all the variability could be due to variation in residence location: urban, rural or pit village. This is investigated and a method introduced which might be useful in assessing the significance of genetic distance results. Edwards’ method of genetic distance is used, together with a nonmetrical scaling procedure, so that the data may be visualized in two dimensions.

Recommended Citation

Cartwright, R A.; Hargreaves, H J.; and Sunderland, E (1977) "Serum Protein and Isoenzyme Polymorphisms from Nottingham, England," Human Biology: Vol. 49: Iss. 4, Article 10.
Available at: https://digitalcommons.wayne.edu/humbiol/vol49/iss4/10