Relationship of Serum Creatine Phosphokinase to Body Composition

Document Type

Article

Authors

Ladislav P. Novak, Southern Methodist University, Dallas, Texas
Glenn Tillery, Baylor University, Dallas, Texas

Abstract

Elevated creatine phosphokinase (CPK) activity in serum can lead to false clinical interpretation in absence of myocardial infarction in patients with large muscle mass due to high CPK, isoenzyme. This study re-examined the relationship of total CPK to body composition in two groups of males.The subjects, 37 healthy males, divided into group A, age 21 to 30 years and group B, age 31 to 40 years. Serum CPK levels were determined on ACA Automatic clinical analyzer. Lean body mass (LBV1) was determined from total body water and known hydration of lean body mass. Corrected diameters were determined to provide further evidence about the relationships of leanness to CPK. The older men had significantly greater weight and slightly greater lean diameters of the limbs. Also, they had a greater absolute amount of lean body mass. However, their relative lean body mass was significantly lower. Similarly, their total CPK was significantly lower. Stepwise regression analysis indicated in both age groups that total CPK is strongly related to the lean body mass expressed in percentage of body weight.

Recommended Citation

Novak, Ladislav P. and Tillery, Glenn (1977) "Relationship of Serum Creatine Phosphokinase to Body Composition," Human Biology: Vol. 49: Iss. 3, Article 12.
Available at: https://digitalcommons.wayne.edu/humbiol/vol49/iss3/12