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A sample of 111 females from the Burlington Growth Centre were studied to evaluate the relationship between craniofacial growth, chronological age, and skeletal age. Two methods of assessing skeletal age (Tanner and Whitehouse, and Greulich and Pyle) and 13 craniofacial measurements were used. The interrelationship of the craniofacial changes to chronological and skeletal age increments, was studied over an interval of approximately eight years. In general, the relationship of changes in both skeletal age and craniofacial measurements, was similar to that between the latter and the chronological age increments. It appears that for clinical purposes, at least in females, craniofacial changes could be as accurately calculated in terms of chronological age changes, except perhaps in those children who are extremely accelerated or seriously delayed in maturation level.