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The fingerprints of 592 normal subjects and 125 patients with Down’s syn­drome have been analyzed in “sets”, a set comprising the 10 fingerprints of one individual. For all pattern types in normals and all except radial loops in Down’s syndrome, the number of persons with few or many patterns of a single Galton type exceeds binomial expectation, while the number in the intermediate range is correspondingly below expectation. These observations demonstrate that the fingerprint patterns are not independently determined, but that the patterns in any one individual tend to be alike.