Department

Biomedical Engineering

Faculty Advisor(s)

Mai T. Lam

Document Type

Poster

Abstract

Adipose-derived Stem Cells (ASC’s) provide an optimal source for potentially graft replacing, tissue-engineered vessel constructs due to their ease of extraction and ability to be patient-specific. In order to make ASC ring constructs a more viable replacement for grafts, they need to have mechanical properties similar to native arteries, which is largely influenced by the extracellular matrix protein collagen. TGFβ-1 is known to stimulate collagen production in ASC’s, so this study explores the effect that TGFβ-1 has on the resulting thickness and tensile strength of ASC ring constructs.

Disciplines

Biomaterials | Molecular, Cellular, and Tissue Engineering

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