Off-campus WSU users: To download campus access theses, please use the following link to log into our proxy server with your WSU access ID and password.
Non-WSU users: Please talk to your librarian about requesting this thesis through interlibrary loan.
Date of Award
In Tribolium, combinatorial knockdown of the Pax6 orthologs eyeless (ey) and twin of eyeless (toy) affects the peripheral visual system but also other areas of the dorsal larval head capsule. To elucidate the role of Pax6 genes during Tribolium embryonic head development in detail, we performed an extensive analysis of cuticle
elements, brain anatomy, embryonic head morphogenesis and developmental marker gene expression. Our results reveal that Pax6 is required for the development of a large contiguous area of the lateral anterior head, morphologically addressed as the embryonic head lobes, which encompass the neuroectodermal precursor tissues of the visual system, parts of the mushroom bodies, and the dorsal head cuticle. In addition to consolidating our understanding of the developmental compartmentalization of the
early Tribolium head, these data characterize Pax6 genes as regional regulators of development.
Luan, Qing, "Pax6 is required for the development of the lateral procephalon in tribolium" (2012). Wayne State University Theses. Paper 196.