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Access Type
WSU Access
Date of Award
January 2011
Degree Type
Dissertation
Degree Name
Ph.D.
Department
Chemistry
First Advisor
John SantaLucia, Jr.
Second Advisor
David Rueda
Abstract
Nucleic acids are good candidates for nanomachine construction. They participate in all the processes of life, and so can function as structural building blocks and dynamic catalysts. However, to use nucleic acids as nanomachines, a better understanding of their material properties, how to design structures using them, and their dynamics is needed. We have tried to address these issues, in a small way, with nucleic acid force field development, an attempt at nanostructural design and synthesis using DNA, and a study of the RNA/protein regulatory dynamics of the tryptophan regulatory attenuation protein.
Recommended Citation
Wood, Marcus, "Artificial and natural nucleic acid self assembling systems" (2011). Wayne State University Dissertations. Paper 298.
http://digitalcommons.wayne.edu/oa_dissertations/298