The coordinated iron structure and ferrochelatase binding surface of human frataxin have been characterized to provide insight into the protein’s ability to serve as the iron chaperone during heme biosynthesis.
Biochemistry | Chemistry | Molecular Biology
Bencze, Krisztina Z.; Yoon, Taejin; Millán-Pacheco, César; Bradley, Patrick B.; Pastor, Nina; Cowan, J. A.; and Stemmler, Timothy L., "Human Frataxin: Iron and Ferrochelatase Binding Surface" (2007). Biochemistry and Molecular Biology Faculty Publications. Paper 14.