We computed mean inbreeding coefficients (FIT, FIS, and FST) based on approximately 2,700 ascending pedigrees of contemporary people from Saguenay Lac-St-Jean (Que´bec, Canada). This allowed us to appreciate the accumulated inbreeding and to follow the evolution of these coefficients since the founding of Que´bec. One of the results was the expected increase in FST. Relying on this parameter, we computed the effective size (Ne) of the contemporary population, obtaining a value around 1,000, in agreement with previous estimations. We noticed a decrease of Ne through history despite the population‘s growing size.
Mourali-Chebil, Soufia and Heyer, Evelyne
"Evolution of Inbreeding Coefficients and Effective Size in the Population of Saguenay Lac-St.-Jean (Que´bec),"
4, Article 7.
Available at: http://digitalcommons.wayne.edu/humbiol/vol78/iss4/7