Haptoglobin Gene Promoter Polymorphism and Haplotypes Are Unique in Different Populations

Document Type

Article

Authors

Kwesi Teye, Kurume University School of MedicineFollow
Mikiko Soejima, Kurume University School of Medicine
Isaac K. E. Quaye, University of Ghana Medical School
Hao Pang, Kurume University School of Medicine

Abstract

We investigated the distribution of haptoglobin (HP) alleles and haplotypes among Africans (Ghanaians), Europeans (from South Africa), and Chinese. HP*1F was present only in Africans and Europeans, whereas HP*del was unique to Chinese. Six base substitutions at the promoter region were population specific. Only 3 out of 18 haplotypes were shared among the populations. A probable application of HP in human population genetics appears legitimate.

Recommended Citation

Teye, Kwesi; Soejima, Mikiko; Quaye, Isaac K. E.; and Pang, Hao (2006) "Haptoglobin Gene Promoter Polymorphism and Haplotypes Are Unique in Different Populations," Human Biology: Vol. 78: Iss. 1, Article 10.
Available at: https://digitalcommons.wayne.edu/humbiol/vol78/iss1/10