Frequencies of the Four Major Amerindian mtDNA Haplogroups in the Population of Montevideo, Uruguay

Document Type

Article

Authors

Cecilia Gascue, Departamento de Citogene´tica, Instituto de Investigaciones Biolo´gicas Clemente Estable, Av. Italia 3318, CP 11600, Montevideo, Uruguay.
Adriana Mimbacas, Departamento de Citogene´tica, Instituto de Investigaciones Biolo´gicas Clemente Estable, Av. Italia 3318, CP 11600, Montevideo, Uruguay., Departamento de Citogene´tica, Unidad Asociada, Instituto de Biologı´a, Facultad de Ciencias, Av. Italia 3318, CP 11600, Montevideo, Uruguay.
Mónica Sans, Seccio´n Antropologı´a Biolo´gica, Facultad de Humanidades y Ciencias de la Educacio´n, Magallanes 1577, CP 11200, Montevideo, Uruguay.
Juan Pablo Gallino, Departamento de Citogene´tica, Instituto de Investigaciones Biolo´gicas Clemente Estable, Av. Italia 3318, CP 11600, Montevideo, Uruguay.
Bernardo Bertoni, Departamento de Gene´tica, Facultad de Medicina, Gral. Flores 2125, CP 11800, Montevideo, Uruguay.
Pedro Hidalgo, Laboratorio de Inmunogene´tica e Histocompatibilidad, Banco Nacional de Organos y Tejidos, Hospital de Clı´nicas ‘‘Manuel Quintela,’’ Av. Italia s/n, CP 11800, Montevideo, Uruguay.
Horacio Cardoso, Departamento de Citogene´tica, Instituto de Investigaciones Biolo´gicas Clemente Estable, Av. Italia 3318, CP 11600, Montevideo, Uruguay.

Abstract

mtDNA Amerindian polymorphisms were studied in 108 inhabitants of Montevideo, Uruguay, using PCR RFLP analysis. Amerindian haplogroups were found in 20.4% of the sample. The frequency of Amerindian polymorphisms in Montevideo differed significantly from that observed in Tacuarembo´, a city about 400 km away, indicating the high level of variation within Uruguay. Results for mitochondrial markers indicate that admixture occurred primarily as a result of Amerindian females mating with European males.

Recommended Citation

Gascue, Cecilia; Mimbacas, Adriana; Sans, Mónica; Gallino, Juan Pablo; Bertoni, Bernardo; Hidalgo, Pedro; and Cardoso, Horacio (2005) "Frequencies of the Four Major Amerindian mtDNA Haplogroups in the Population of Montevideo, Uruguay," Human Biology: Vol. 77: Iss. 6, Article 10.
Available at: https://digitalcommons.wayne.edu/humbiol/vol77/iss6/10