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Article

Hong Wu, Laboratory of Human Population Genetics and Complex Diseases, Institute of Genetics, Fudan University, Shanghai, China.,
Hong Wang, Laboratory of Human Population Genetics and Complex Diseases, Institute of Genetics, Fudan University, Shanghai, China., Institute of Dermatology, National Academy of Medical Sciences, Nanjing, China.
Hui Li, Laboratory of Human Population Genetics and Complex Diseases, Institute of Genetics, Fudan University, Shanghai, China.
Joshua Akey, Human Genetics Center, School of Public of Health, University of Texas - Houston, Houston, Texas.
Fengyuan Xiao, Human Genetics Center, School of Public of Health, University of Texas - Houston, Houston, Texas.
Yuehai Ke, Laboratory of Human Population Genetics and Complex Diseases, Institute of Genetics, Fudan University, Shanghai, China.
Hongyan Yu, Laboratory of Human Population Genetics and Complex Diseases, Institute of Genetics, Fudan University, Shanghai, China.
Junhua Xiao, Laboratory of Human Population Genetics and Complex Diseases, Institute of Genetics, Fudan University, Shanghai, China.
Daru Lu, Laboratory of Human Population Genetics and Complex Diseases, Institute of Genetics, Fudan University, Shanghai, China.
Esteban Parra, Department of Anthropology, Pennsylvania State University, University Park, Pennsylvania.
Mark Shriver, Department of Anthropology, Pennsylvania State University, University Park, Pennsylvania.
Momiao Xiong, Human Genetics Center, School of Public of Health, University of Texas - Houston, Houston, Texas.
Sara A. Barton, Human Genetics Center, School of Public of Health, University of Texas - Houston, Houston, Texas.
David Hewett-Emmett, Human Genetics Center, School of Public of Health, University of Texas - Houston, Houston, Texas.
Weida Liu, Institute of Dermatology, National Academy of Medical Sciences, Nanjing, China.
Li Jin, Laboratory of Human Population Genetics and Complex Diseases, Institute of Genetics, Fudan University, Shanghai, China., Human Genetics Center, School of Public of Health, University of Texas - Houston, Houston, Texas.

Abstract

Genetic and environmental factors are involved in the determination of skin pigmentation in humans. With the recent development of statistical and genetic tools in mapping complex traits in humans, it is becoming feasible to utilize such methods in identifying genes involved in skin pigmentation. Furthermore, the use of new portable reflectance spectroscopy instruments such as the Photovolt ColorWalk colorimeter allows researchers to measure skin reflectance of a large number of subjects with ease and accuracy. We used a new portable instrument (Photovolt ColorWalk) to study the skin reflectance of 372 Han Chinese and 274 Tibetan individuals to establish background reflectance measurements of unexposed skin of the inner upper arm in these two populations. In addition, we explored the effect of various factors such as age and gender on skin reflectance.

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