We determined acetylator phenotypes by means of a sulfadimidine test and found that 39% of the native population of the province of Jujuy, in northwestern Argentina, have slow acetylators. The frequency of the allele controlling slow acetylation was estimated at q = 0.65 ± 0.001. This estimate differs from those previously recorded in native and Mestizo American populations. A review of the literature on acetylator phenotypes in the Americas revealed that it is not possible to discern any clear pattern of distribution in relation to the geographic variability observed.
Dipierri, Jose Edgardo; Alfaro, Emma; Bejarano, Ignacio Felipa; and Etchart, Ana Alicia
"Acetylator Phenotypes: Allele Frequency in Northwestern Argentina and Review of Acetylator Distribution in the Americas,"
5, Article 9.
Available at: http://digitalcommons.wayne.edu/humbiol/vol70/iss5/9