When analyzed by origin, the frequency of the DF508 mutation (the main cystic fibrosis mutation) varies between population groups. We show here that the frequency of the DF508 mutation varies among different populations, being higher in northwest Europeans than in southeast European populations. The map we have constructed covers 25 countries; isofrequency curves were calculated using an original method.
Lucotte, Gérard and Loirat, France
"Breif Communication: A More Detailed Map of the Cystic Fibrosis Mutation DF508 Frequencies in Europe,"
3, Article 11.
Available at: http://digitalcommons.wayne.edu/humbiol/vol65/iss3/11