The identification of a null allele in a human genetic system restricted to the placenta is a great challenge for two reasons: the impossibility of carrying out family studies and the unviability of sample recollections because the placenta itself is a disposable universe. Thus, in addition to reporting the finding of a null phenotype of placental alkaline phosphatase in a dark mulatto newborn from a black mixed population of Bahia, Brazil, here we present other evidence for the presence of the ALPP*Q0 allele with considerably high frequency in this population.
Silva, M. C.B.O.; Sousa, M. G.F.; Carvalho, R. D.S.; Passos-Bueno, M. R.; and Azevêdo, E. S.
"Null Allele in a Human Polymorphism Restricted to the Placenta: Call for a Search,"
2, Article 5.
Available at: http://digitalcommons.wayne.edu/humbiol/vol63/iss2/5