Null Allele in a Human Polymorphism Restricted to the Placenta: Call for a Search

Document Type

Article

Authors

M. C.B.O. Silva, Universidade Federal da Bahia, Brazil
M. G.F. Sousa, Universidade Federal da Bahia, Brazil
R. D.S. Carvalho, Universidade Federal da Bahia, Brazil
M. R. Passos-Bueno, Universidade Federal da Bahia, Brazil
E. S. Azevêdo

Abstract

The identification of a null allele in a human genetic system restricted to the placenta is a great challenge for two reasons: the impossibility of carrying out family studies and the unviability of sample recollections because the placenta itself is a disposable universe. Thus, in addition to reporting the finding of a null phenotype of placental alkaline phosphatase in a dark mulatto newborn from a black mixed population of Bahia, Brazil, here we present other evidence for the presence of the ALPP*Q0 allele with considerably high frequency in this population.

Recommended Citation

Silva, M. C.B.O.; Sousa, M. G.F.; Carvalho, R. D.S.; Passos-Bueno, M. R.; and Azevêdo, E. S. (1991) "Null Allele in a Human Polymorphism Restricted to the Placenta: Call for a Search," Human Biology: Vol. 63: Iss. 2, Article 5.
Available at: https://digitalcommons.wayne.edu/humbiol/vol63/iss2/5