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Theses/Dissertations from 2017

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Development Of Tools For Phosphosite-Specific Kinase Identification And Discovery Of Phosphatase Substrates, Pavithra Maheshani Dedigama Arachchige

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The Development Of Chemical Methods To Discover Kinase Substrates And Map Cell Signaling With Gamma-Modified Atp Analog-Dependent Kinase-Catalyzed Phosphorylation, Dissanayaka Mudiyanselage Maheeka Madhubashini Embogama

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A New Three-Dimensional (3d) Particle Coincidence Imaging System And Its Applications In Strong Field Studies Of Reaction Dynamics In Atoms And Molecules, Yunfei Lin

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Gas-Phase Ion Spectroscopy Of Nucleobases And Mononucleotides: Models For Higher Order Nucleic Acids, Yuan-Wei Nei

Theses/Dissertations from 2016

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Studying The Atp Cosubstrate Promiscuity Of Nucleotide And Lipid Kinases, Thilani Murium Anthony

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Synthesis Of Dinucleating Ligands And Their Dinuclear Metal Complxes:applications In Sensing And Small Molecule Activation, Jeffrey William Beattie

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Design Of First-Row Transition Metal Bis(alkoxide) Complexes And Their Reactivity Toward Nitrene And Carbene Transfer, James Bellow

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Development Of New Algorithms For Exploring The Potential Energy Landscape Of Chemical Reactions, Adam Benjamin Birkholz

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Biological Evaluation Of The Vaccine Candidate Tf-Ps A1 And A One-Pot Multicomponent Coupling/cyclization For Natural Product Herbicide (±)-Thaxtomin A, Jean Paul Bourgault

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Chalcogenide Nanocrystal Assembly: Controlling Heterogeneity And Modulating Heterointerfaces, Jessica Davis Davis

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Europium(ii)-Containing Complexes For Responsive Magnetic Resonance Imaging, Levi Alexander Ekanger

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State Resolved Sliced Imaging Of Infrared Multiphoton Dissociation, Ravin Lakshitha Fernando

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Development Of Gamma-Modified Atp Analogs To Study Kinase-Catalyzed Phosphorylations, Ahmed Eid Fouda

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Synthesis, Characterization, And Properties Of Peroxo-Based Oxygen-Rich Compounds For Potential Use As Greener High Energy Density Materials, Nipuni-Dhanesha Horadugoda Gamage

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New Approaches To Chalcogenide Materials For Thermoelectrics: Lead Telluride-Based Nanostructures And Facile Synthesis Of Tetrahedrite And Doped Derivatives, Derak Justin James

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Electron Transfer Studies In Langmuir-Blodgett Films Of Metallosurfactants For Current Rectification, Corrosion Mitigation, And Water Oxidation, Sunalee Gonawala Jayasundara Mudiyanselage

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New Chemistry For The Growth Of First-Row Transition Metal Films By Atomic Layer Deposition, Joseph Peter Klesko

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Use Of 17o-Nmr Spectroscopy To Study The Coordination Chemistry Of Trivalent Lanthanide Ions In Solution, Zhijin Lin

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Synthesis And Characterization Of Transition Metal Phosphide Nanoparticles For Catalytic Applications: Model Catalysts For Hydrodesulfurization And Electrocatalysts For The Oxygen Evolution Reaction, Don Malinda Ruchira Liyanage

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Synthesis Of Apramycin And Paromomycin Derivatives As Potential Next Generation Aminoglycoside Antibiotics And Chemistry Of Isothiocyanato Sialyl Donors, Appi Reddy Mandhapati

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Studies Towards Broadening The Substrate Profile And Regulation Of Histone Deacetylase 1, Dhanusha Ashanthi Nalawansha

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A Novel, Ultra-Fast Electrochemical Tool To Study Speciation Of Trace Metals In Aqueous Solution, Pavithra Pathirathna

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Synthesis And Heteroallene Reactivity Of Bis(aldimino)pyridine Nickel Complexes In Four Different Oxidation States, Blake Reed

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Synthesis And Biological Evaluation Of Nitrile-Based Inhibitors Of Cysteine Proteases Caged With Ruthenium Complexes, Rajgopal Sharma

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How Geometric Distortions Scatter Electronic Excitations In Conjugated Macromolecules: Towards Photoinduced Relaxation And Energy Transfer, Tian Shi

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Crossed Beam Imaging Of The Reaction Dynamics Of Halogen Atoms With Selected Hydrocarbons, Yuanyuan Shi

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Development Of A Novel Class Of Chemicals For Labeling Abasic Sites In Cellular Dna And Killing Cancer Cells, Shanqiao Wei

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Studies Toward A Detailed Understanding Of The Intrinsic Properties Of Nucleic Acid Constituents: Gas-Phase Conformations, Energetics, And Glycosidic Bond Stability, Ranran Wu

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Development Of Single And Array Electro-Chemical Sensors For Real-Time Trace Metal Analysis In Aqueous Environmental Media, Yuanyuan Yang

Theses/Dissertations from 2015

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Chirped-Pulse Fourier Transform Microwave Spectroscopy In Pulsed Uniform Supersonic Flows, Chamara S.w Abeysekera

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(i)chromatographic Methods For Solute Descriptor Determinations (ii)ruthenium Substrate-Catalyzed Growth Of Nickel Nitride Thin Films By Atomic Layer Deposition, Thiloka Chandima Ariyasena

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Noncovalent Interactions Between Alkali Metal Cation And Aza/thia-Crown Macrocycles: Mass Spectrometric Techniques And Theoretical Studies, Calvin A. Austin

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Synthesis, Characterization, And Rna Reactivity Of Amino-Acid-Linked Cisplatin Analogues, Xun Bao

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Investigation Of New Ligand Architechtures Towards Proton And Water Reduction Catalysis By Cobalt Complexes, Debashis Basu

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Strong Field Ionization Of Radicals And Reaction Intermediates, Fadia Cudry

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Platination Kinetics: Insight Into Rna-Cisplatin Interactions As A Probe For Rna Microenvironments, Gayani Dedduwa-Mudalige

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The Development Of Peptide Ligands To Target H69 Rrna, Danielle Nicole Dremann

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Biochemical And Structural Characterization Of The Core Subunits Of Gpi Transamidase, Dilani G. Gamage

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Developing A Toolbox To Probe Reaction Dynamics With Strong Field Ionization And Non-Linear Attosecond Spectroscopy, Thushani Nikeshala Herath

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Dna Aptamers Selected Against Wild-Type Helix 69 Ribosomal Rna And Their Implications In Combating Antibiotic Resistance, Sakina Miriam Hill

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Ln(ii)-Containing Cryptates: Synthesis And Properties, Akhila Nuwan Wijerathne Kuda-Wedagedara

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The Loss Of Genomic Uracil Homeostasis And Aid-Dependent Accumulation Of Dna Damage In B Cell Lymphomas, Sophia Shalhout

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On The Nature Of Excited States In Ruthenium Complexes: Towards Renewable Energy, Ryan A. Thomas

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Classical And Ab Initio Qm/mm Simulations Of Bacterial Enzymes, Sajeewa Walimuni Dewage

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Development Of Inlet And Vacuum Ionization Methods For Characterization Of Biological Materials By Mass Spectrometry, Beixi Wang

Theses/Dissertations from 2014

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Evaluation Of Presynaptic Dopamine Dynamics After: Toluene Inhalation Or Trkb Receptor Activation, Aaron Kwaku Apawu

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Lanthanide-Based Precatalysts For Carbon-Carbon Bond-Forming Reactions In Aqueous Media, Derek James Averill

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Rydberg Time-Of-Flight And Imaging Probes Of The Velocity-Dependent Hydrogen Atom Spin Polarization, Bernadette Michlewicz Broderick

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Computational Studies Of Enzymatic Reactions And Inorganic Compounds, Dong Fang

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Structural And Functional Characterization Of Proteins Of Unknown Function (hp0495, Hp0100 And Hp1259) In Helicobacter Pylori, Shirin Fatma

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Investigation Into The Binding Interactions Of Klenow Fragment To Dna Modified With Carcinogens Af And Aaf Using Surface Plasmon Resonance, Ashley M. Floyd

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Synthesis And Characterization Of Discrete Fexni2-Xp Nanoparticles; Assembly Of Phosphide Nanoparticles Into Porous Networks, Asha Hitihami Mudiyanselage

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Precursors And Processes For The Growth Of Metallic First Row Transition Metal Films By Atomic Layer Deposition, Lakmal Charidu Kalutarage

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Hiv-1 Rna Dimerization At Single Molecule Level, Hansini R. Mundigala

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Alterations In The Mouse Striatum Following Acute And Repeated Ethanol Exposure, Brooke D. Newman

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Experimental And Theoretical Studies Of Binding Interactions In Divalent Transition Metal Cation-N-Donor Ligand Complexes: Structures, Sequential Bond Dissociation Energies, Mechanisms And Energetics Of Collision-Induced Dissociation, Holliness Nose

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Development Of Elisa-Based Hdac Activity Assay For Identification Of Isoform Selective Hdac Inhibitors, Geetha Padige

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Assembly And Function Of Macromolecular Complexes For Accurate Trna Aminoacylation In Helicobacter Pylori, Gayathri Niroshani Silva

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Modulation Of Water-Exchange Rates Of Lanthanide(iii)-Containing Complexes Using Polyethylene Glycol, Buddhima Nirodhi Siriwardena-Mahanama

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Probing Proteasome Inhibition By Metal Copmplexes As A New Route For Anticancer Therapy, Dajena Tomco

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Synthesis And Characterization Of New Gd3+-Containing Complexes As Potential Targeted Contrast Agents For Magnetic Resonance Imaging, Sashiprabha Manjari Vithanarachchi

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Redox-Active Trivalent Metallosurfactants With Low Global Symmetry For Molecule-Based Electronics: Spectroscopic, Electrochemical, And Amphiphilic Properties Of New Molecular Materials For Current-Voltage Measurements In M|lb-Monolayer|m Devices, Lanka Dilruksi Wickramasinghe Wickramasinghe Arachchilage

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Theoretical And Experimental Studies Of Noncovalent Metal Cation Binding And Base Pairing Interactions Of Cytosine And Modified Cytosines, Bo Yang

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New Carbohydrate-Based Anti-Cancer And Anti-Bacterial Vaccines, Zhifang Zhou

Theses/Dissertations from 2013

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Development Of Peptide Inhibitors Targeting Clostridium Difficile Toxins A/b And Characterizing The Regulatory Role Of A Putative Negative Regulator Tcdc In Clostridium Difficile Toxin Gene Expression, Sanofar Jainul Abdeen

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Development And Optimization Of The First High Throughput In Vitro Fret Assay To Characterize The Saccharomyces Cerevisiae Gpi-T, Sandamali Amarasingha Ekanayaka

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Investigation Of Dopamine Dynamics In Bdnf+/- Mice Using In Vivo Microdialysis And Electrochemical Analysis Of Purine And Monoamine Molecules Using A Boron-Doped Diamond Electrode, Johnna A. Birbeck

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1. Chromium(0)- Promoted Higher Order Cycloaddition Reactions: Studies Toward The Total Synthesis Of The Cyclocitrinols And Echinopines A And B 2. Total Synthesis Of (±)-Debromoflustramine B Via [4+1] Cyclization Of An Indole Isocyanate And A Bis(alkylthio)carbene, Saptarshi De

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Investigating Hfq-Mrna Interactions In Bacteria, Martha Audra Faner

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Studies On The Physicochemical Properties Of Eu2+ Cryptates: Implications To Contrast Agents For Magnetic Resonance Imaging, Joel Garcia

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Synthesis And Application Of Atp Analogs For Phosphorylation-Dependent Kinase-Substrate Crosslinking, Satish Kumar Garre Venkata Raghavendra

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Development Of Matrix Assisted Ionization Methods For Characterization Of Soluble And Insoluble Proteins From Native Environments By Mass Spectrometry, Ellen Dela Victoria Inutan

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Striatal Dopamine Dynamics Upon Manganese Accumulation, Madiha Khalid

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Chalcogenide Sol-Gel Assembly: Controlling The Kinetics Of Nanocrystal Aggregation And Film Formation For Applications In Optoelectronics, Lasantha Korala

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Design, Synthesis, And Luminescence Properties Of Bridged Dimetallic Lanthanide Coordination Compounds, Jeremiah David Moore

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Single-Molecule Studies Of Local And Global Nucleic-Acid Dynamics, Eric Muthuri Patrick

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Exploring Molecular Systems From Chemical Physics To Biochemistry Using Classical And Quantum Mechanics, Brian Thomas Psciuk

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Methodologies For Attaching Polypyridyl Ligands Into Amino Acids And Synthesis And Biological Evaluation Of Novel Light Activated Peptidomimetic Cysteine Protease Inhibitors Caged By Ruii(bpy)2, Tomasz Respondek

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Single-Stranded Dna Scanning And Deamination With Single-Molecule Resolution, Padhuk Gamarala Senavirathne

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Development Of Kinase Catalyzed Biotinylation To Study Phosphoproteomics, Kona Arachchilage Chamara Indunil Bandara Senevirathne

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Synthesis And Characterization Of Metal Complexes Containing Tetrazolate, Poly(tetrazolyl)borate, And Poly(azolyl)aluminate Ligands As High Energy Density Materials, Christopher James Snyder

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Computational Approaches To Anti-Toxin Therapies And Biomarker Identification, Rebecca Jane Swett

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Unveiling Dna Polymerase Synthesis And Proofreading Activities - One Molecule At A Time, Kyle Vrtis

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Histone Deacetylase 1: Mutagenesis And Small Molecule Studies, Magdalene Wambua

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Development Of Ruthenium/terpyridine Complexes For Water Oxidation, Dakshika Chandrashani Wanniarachchi

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Fundamental Studies And Applications Of Strong Field Ionization, Lu Yan

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Synthesis And Characterization Of Transition Metal Arsenide Nanocrystals And The Metastability And Magneto-Structural Phase Transition Behavior Of Mnas Nanocrystals, Yanhua Zhang

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Enzymatic Characterization Of The Ammonia Tunnel In Helicobacter Pylori Asp-Trnaasn/glu-Trnagln Amidotransferase, Liangjun Zhao

Theses/Dissertations from 2012

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Development of an electrospary ionization source and vacuum interface for guided ion beam tandem mass spectrometry experiments: structural and energetic effects in the molecular recognition of amino acids by 18-crown-6, Yu Chen

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The structural requirements of histone deacetylase (hdac) inhibitors: suberoylanilide hydroxamic acid (saha) analogues modified at c3, c6, and c7 positions enhance selectivity, Sun ea Choi

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New adaptations of analytical tools for the study of dynamic interactions of lanthanide-based catalysis in aqueous media, Prabani Lakmanthi Dissanayake

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Probing the dynamics of radical reactions with polyatomic hydrocarbons by crossed-beam dc slice imaging, Armando Dura Estillore

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Transfer rna dynamics and transfer-messenger rna accommodation in bacterial ribosomes at the single-molecule level, May Daher Farhat

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State-resolved slice imaging of photochemical dynamics, Herath mudiyans nuradhika Herath

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"fine-tuning" of ribosomal structure and functions by pseudouridylation and rna-protein interactions, Jun Jiang

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Determination of descriptors by liquid-liquid partition and chromatographic methods, Thushara Namal Karunasekara

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Development of a cargo delivery system and inhibition studies focused on clostridium difficile toxin a, Stephanie Marie Kern

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New precursors and chemistry for the growth of transition metal films by atomic layer deposition, Thomas Joseph Knisley

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Synthesis, spectroscopic, and electrochemical properties of 3d metal and ruthenium complexes with phenolate and catecholate ligands, Frank Donald Lesh

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Effect of low endogenous brain-derived neurotrophic factor levels on striatal dopamine dynamics, Francis Kabui Maina