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Theses/Dissertations from 2013

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Development Of Peptide Inhibitors Targeting Clostridium Difficile Toxins A/b And Characterizing The Regulatory Role Of A Putative Negative Regulator Tcdc In Clostridium Difficile Toxin Gene Expression, Sanofar Jainul Abdeen

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Development And Optimization Of The First High Throughput In Vitro Fret Assay To Characterize The Saccharomyces Cerevisiae Gpi-T, Sandamali Amarasingha Ekanayaka

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Investigation Of Dopamine Dynamics In Bdnf+/- Mice Using In Vivo Microdialysis And Electrochemical Analysis Of Purine And Monoamine Molecules Using A Boron-Doped Diamond Electrode, Johnna A. Birbeck

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1. Chromium(0)- Promoted Higher Order Cycloaddition Reactions: Studies Toward The Total Synthesis Of The Cyclocitrinols And Echinopines A And B 2. Total Synthesis Of (±)-Debromoflustramine B Via [4+1] Cyclization Of An Indole Isocyanate And A Bis(alkylthio)carbene, Saptarshi De

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Investigating Hfq-Mrna Interactions In Bacteria, Martha Audra Faner

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Studies On The Physicochemical Properties Of Eu2+ Cryptates: Implications To Contrast Agents For Magnetic Resonance Imaging, Joel Garcia

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Synthesis And Application Of Atp Analogs For Phosphorylation-Dependent Kinase-Substrate Crosslinking, Satish Kumar Garre Venkata Raghavendra

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Development Of Matrix Assisted Ionization Methods For Characterization Of Soluble And Insoluble Proteins From Native Environments By Mass Spectrometry, Ellen Dela Victoria Inutan

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Striatal Dopamine Dynamics Upon Manganese Accumulation, Madiha Khalid

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Chalcogenide Sol-Gel Assembly: Controlling The Kinetics Of Nanocrystal Aggregation And Film Formation For Applications In Optoelectronics, Lasantha Korala

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Design, Synthesis, And Luminescence Properties Of Bridged Dimetallic Lanthanide Coordination Compounds, Jeremiah David Moore

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Single-Molecule Studies Of Local And Global Nucleic-Acid Dynamics, Eric Muthuri Patrick

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Exploring Molecular Systems From Chemical Physics To Biochemistry Using Classical And Quantum Mechanics, Brian Thomas Psciuk

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Methodologies For Attaching Polypyridyl Ligands Into Amino Acids And Synthesis And Biological Evaluation Of Novel Light Activated Peptidomimetic Cysteine Protease Inhibitors Caged By Ruii(bpy)2, Tomasz Respondek

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Single-Stranded Dna Scanning And Deamination With Single-Molecule Resolution, Padhuk Gamarala Senavirathne

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Development Of Kinase Catalyzed Biotinylation To Study Phosphoproteomics, Kona Arachchilage Chamara Indunil Bandara Senevirathne

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Synthesis And Characterization Of Metal Complexes Containing Tetrazolate, Poly(tetrazolyl)borate, And Poly(azolyl)aluminate Ligands As High Energy Density Materials, Christopher James Snyder

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Computational Approaches To Anti-Toxin Therapies And Biomarker Identification, Rebecca Jane Swett

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Unveiling Dna Polymerase Synthesis And Proofreading Activities - One Molecule At A Time, Kyle Vrtis

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Histone Deacetylase 1: Mutagenesis And Small Molecule Studies, Magdalene Wambua

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Fundamental Studies And Applications Of Strong Field Ionization, Lu Yan

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Synthesis And Characterization Of Transition Metal Arsenide Nanocrystals And The Metastability And Magneto-Structural Phase Transition Behavior Of Mnas Nanocrystals, Yanhua Zhang

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Enzymatic Characterization Of The Ammonia Tunnel In Helicobacter Pylori Asp-Trnaasn/glu-Trnagln Amidotransferase, Liangjun Zhao

Theses/Dissertations from 2012

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Development of an electrospary ionization source and vacuum interface for guided ion beam tandem mass spectrometry experiments: structural and energetic effects in the molecular recognition of amino acids by 18-crown-6, Yu Chen

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The structural requirements of histone deacetylase (hdac) inhibitors: suberoylanilide hydroxamic acid (saha) analogues modified at c3, c6, and c7 positions enhance selectivity, Sun ea Choi

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New adaptations of analytical tools for the study of dynamic interactions of lanthanide-based catalysis in aqueous media, Prabani Lakmanthi Dissanayake

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Probing the dynamics of radical reactions with polyatomic hydrocarbons by crossed-beam dc slice imaging, Armando Dura Estillore

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Transfer rna dynamics and transfer-messenger rna accommodation in bacterial ribosomes at the single-molecule level, May Daher Farhat

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Synthesis and characterization of metal chalcogenide nanostructured materials for thermoelectric applications, Shreyashi Ganguly

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State-resolved slice imaging of photochemical dynamics, Herath mudiyans nuradhika Herath

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"fine-tuning" of ribosomal structure and functions by pseudouridylation and rna-protein interactions, Jun Jiang

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Determination of descriptors by liquid-liquid partition and chromatographic methods, Thushara Namal Karunasekara

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Development of a cargo delivery system and inhibition studies focused on clostridium difficile toxin a, Stephanie Marie Kern

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New precursors and chemistry for the growth of transition metal films by atomic layer deposition, Thomas Joseph Knisley

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Synthesis, spectroscopic, and electrochemical properties of 3d metal and ruthenium complexes with phenolate and catecholate ligands, Frank Donald Lesh

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Synthesis Of Oligosaccharide Mimetics By The Desulfurative Rearrangement Of Allylic Disulfides And Stereoelectronic Influence Of C-O Bonds On C- And O-Glycosylation, Myriame Moume-Pymbock

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Synthesis And Á-Stereoselective Sialylation Of Kdn And Late Stage Modification Of Neuraminic Acid Sialosides, Chandra Sekhar Navuluri

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Metal chalcogenide nanoparticle gel networks: their formation mechanism and application for novel material generation and heavy metal remediation via cation exchange reactions, Irina Ramona Pala

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Synthesis And Characterization Of Group 5 Metal Complexes Containing Pyrazolate, Amidate, And Related Ligands As Potential Precursors For Thin Film Growth By Atomic Layer Deposition, Thuduwage Hiran Perera

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Metal complexes of non-heme ligands: biological applications, Jai Prakash

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Exploring conformational variability of an rna domain in the ribosome: from structure and function to potential antibiotic targeting, Yogo Sakakibara

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Modes and mechanisms of hfq mediated stress regulation in bacteria, Nilshad Nilam Salim

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Synthesis And Characterization Of Size Controlled Transitionmetal Phosphide Nanoparticles And Their Hydrodesulfurization Catalytic Activity, Galbokka Hewage Layan Savithra

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Synthesis, redox properties, and langmuir monolayer formation of selected 3d- and 4d- metalloamphiphiles, Sree Ramadevi Shanmugam

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Applications of electronic structure theory to problems in strong-field chemistry, inorganic chemistry, and nanomaterial systems, Jason Anthony Sonk

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Genetic and biochemical studies of human apobec family of proteins, Priyanga Wijesinghe

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Single molecule studies of rna-target interactions, Sharla Leann Wood

Theses/Dissertations from 2011

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Method Development And Applications To Screening And Characterization Of Rrna-Targeting Small Molecules, Papa Nii Asare-Okai

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Development of chemical inducers of dimerization for screening competitive histone deactelyase inhibitors, Emily Lynn Aubie

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Synthesis Of N-Acetyl And C-Tert-Butyl Natural Amino Acid Substrates That Mimic Residues Of Polypeptides And Their Reactivity With [feiv(o)(n4py)]2+: Kinetic And Mechanistic Investigations, Ashley Ann Campanali

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New insights into the mechanism of dna replication on unmodified and benzo[a]pyrene modified templates using surface plasmon resonance, Richard George Federley

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Astrochemical dynamics: Fundamental studies relevant to titan's atmosphere, Wilson Kamundia Gichuhi

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Synthesis of peptide-ligand conjugates and their applications, Nitinkumar Dilipkumar Jabre

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Characterization of splicing mechanisms by single-molecule fluorescence, Krishanthi Sanjeewani Karunatilaka

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Isolation And Analysis Of Peptides Binding To Helix 69 Of E. Coli 23 S Rrna From M13 Phage Display, Moninderpal Kaur

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Study Of Protein-Rna Interactions Using Fluorescence Resonance Energy Transfer (fret) And Single-Molecule Fret, Rajan Lamichhane

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Electronic excitations in branched conjugated oligomers: A quasiparticle view and tight-binding models, Hao Li

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Nmr Solution Structures Of Two Hairpins Of E. Coli 16s Rrna: The Effects Of Mutations And Chemical Modifications On Structure And Function Of Rrna, Yu Liu

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Effect of low endogenous brain-derived neurotrophic factor levels on striatal dopamine dynamics, Francis Kabui Maina

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Exploring Potential Drug Target Sites In The Ribosome Using Cisplatin And Its Analogues, Keshab Rijal

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Thiomaleic anhydride: a linchpin for organic synthesis and structural verification of a nonprotein antifreeze oligosaccharide, Md yeajur Rahaman Sardar

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Chemical Synthesis Of Peptides And Peptide Thioesters, Indrajeet Sharma

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Artificial and natural nucleic acid self assembling systems, Marcus Wood

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Laser-assisted single-molecule refolding, Rui Zhao

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Applications Of Electronic Structure Theory To Problems In Unimolecular Dissociation And Inorganic And Biochemical Systems, Jia Zhou

Theses/Dissertations from 2010

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Transition Metal-Mediated Higher-Order Cycloaddition Reactions: Application To The Total Synthesis Of Complex Natural Products, Bilal Abou Aleiwi

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I-Kinetic And Mechanistic Investigations Of Amino Acid Substrates Reactivities With Ferryl Species, Ahmed Ibrahim Youssef Abouelatta

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Experimental And Theoretical Analysis Of The Electronic Behavior In Five-Coordinate Iron(iii) And Six-Coordinate Cobalt(iii) Complexes With Electroactive Phenol-Rich Ligands, Marco Mathieu Allard

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The Effect Of An Intermittent Manganese (ii) Exposure On The Striatal Dopamine System, Rabab Adel Aoun

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Single Molecule Studies Of Spliceosomal Snrnas U2-U6, Zhuojun Guo

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Synthesis And Characterization Of Metal Complexes Containing Tetrazolate, Poly(tetrazolyl)borate, And Aryl Pentazole Ligands As High Energy Density Materials, Dongmei Lu

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Synthetic Levers Enabling Control Of Phase, Size And Morphology In Transition Metal Phosphide Nanoparticles (fe, Ni), Elayaraja Muthuswamy

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The Synthesis, Structure, And Properties Of Group 2 Poly(pyrazolyl)borates And Their Use For The Atomic Layer Deposition Of Group 2 Borates, Mark J. Saly

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Development And Applications Of Thioacids In Peptide Chemistry And Exploration Of Methods Toward The Stereochemical Elucidation And Synthesis Of Virgineone, Kasinath Sana

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I. Microwave-Influenced Diversity-Oriented Synthesis Of Biologically Relevant Small & Natural-Product-Like Molecules Via Multicomponent Coupling Reactions Ii. Synthetic Studies Toward The Total Synthesis Of The Repeating Tetrasaccharide Unit Of Zwitterionic Polysaccharide Ps A1, Soumava Santra

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Photodissociation Dynamics In Titan's Atmosphere, Welvidanalage Ruchira Silva

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Dechalcogenative Allylic Selenosulfide And Disulfide Rearrangements For Cysteine Modification And Glycoligation, Venkataraman Subramanian

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Synthesis Of Functionalized Gpi Anchors And Related Glycoconjugates, Benjamin M. Swarts

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Metal Chalcogenide Nanocrystal Assembly: From Synthesis To Applications, Qinghong Yao

Theses/Dissertations from 2009

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Isothermal Titration Calorimetry Studies Of Protein-Mediated Interactions And Preliminary Structural Studies Of Tandem Pdz1-2 Domain Of Psd-95 Protein, Ana Jankovic