Theses/Dissertations from 2022
Characterizing The Post-Translational Modifications Of The Pro-Oncogenic Type Ii Transmembrane Serine Protease Tmprss13, Carly Elizabeth Martin
Xpo1 As A Therapeutic Target In Gastric Cancer, Rachel Sexton
Theses/Dissertations from 2021
Therapeutic Dual-Targeting Of Cytosolic And Mitochondrial One-Carbon Metabolism, Aamod Sanjeev Dekhne
Clinical Significance, Functional Role And Molecular Mechanism Of 2’-O-Methyltransferase Ftsj3 In Promoting Cancer Progression, Morenci Manning-Powell
Pak4-Nampt Dual Inhibition As A Novel Strategy For Therapy Resistant Pancreatic Neuroendocrine Tumors, Gabriel Benyomo Mpilla
Targeting Metabolic Vulnerabilities In Epithelial Ovarian Cancer Via Folate Transporters, Adrianne Wallace-Povirk
Theses/Dissertations from 2020
The Role Of Bca2 In Regulation Of Warburg-Like Glucose And Lactate Metabolism In Breast Cancer Cell Lines, Richard T. Arkwright Iii
Evaluation Of Autoantibodies To Paraneoplastic Antigens As Early Detection Biomarkers For High-Grade Serous Ovarian Cancer, Laura Catherine Hurley
Theses/Dissertations from 2019
Novel Insights Into The Use Of Ercc1 As A Biomarker For Response To Platinum-Based Chemotherapy In Lung Cancer, Joshua Ryan Heyza
Strategies To Enhance The Anti-Leukemic Activity Of Venetoclax (abt-199) In Aml Through Targeting Of Mcl-1, Daniel Luedtke
Utilizing Immunopet To Measure Tumor Response To Treatment In Breast Cancer, Brooke Mcknight
Investigation Of The Role For Methyl-Cpg Binding Protein 2 Variant Mbd2_v2 In Cancer Stem Cells And Obesity-Associated Cancers, Emily A. Teslow
Theses/Dissertations from 2018
Identifying The Role Of The Type-Ii Transmembrane Serine Protease Tmprss13 In Breast Cancer, Andrew Stevan Murray
Theses/Dissertations from 2017
Pet Imaging Of Early Therapeutic Response In Solid Tumors, Stephanie J. Blocker
The Effects Of Bone Marrow Adipocytes On Metabolic Regulation In Metastatic Prostate Cancer, Jonathan Diedrich
Preparation And Utility Of Polymeric Nanoparticles For The Delivery Of Sirna As Cancer Therapy, Daniel Paul Feldmann
Functional Analysis Of Rad6 In Brca1 Wild Type And Brca1 Mutant Triple Negative Breast Cancer Drug Response, Brittany Haynes
Clinicopathology And Molecular Determinants Underlying Benign Breast And Breast Cancer Lesions, Andreana Holowatyj Holowatyj
Mechanisms Of Hormonal Regulation Of Invasiveness And Metastasis Of Luminal Breast Cancer, Thomas Mcfall
New Mechanism Based Approaches For Treating Prostate Cancer, Rayna Rosati
Functions Of Atr/mec1 In Meiosis And The Cell Cycle, Layne Weatherford
Theses/Dissertations from 2016
Identifying Mechanisms Of Resistance And Potential Therapeutic Targets For Pediatric Acute Myeloid Leukemia, John Timothy Caldwell
Whsc1l1 Regulates Estrogen Receptor Activity In Sum44 Breast Cancer Cells, Jonathan Curtis Irish
Imaging Anti-Proliferative Compounds With Flt-Pet, Christopher Mchugh
Loss Of Rap1gap: A Driver In The Progression From Dcis Of The Breast To Idc, Seema Shah
Structural Characterization And Therapeutic Utility Of The Proton-Coupled Folate Transporter, Michael Roy Wilson
Theses/Dissertations from 2015
Therapeutic Targeting Of Bmp2 In Nf1-Deficient Malignant Peripheral Nerve Sheath Tumors (mpnsts), Sidra Ahsan
Hrd1 Partners In Endoplasmic Reticulum-Associated Degradation, Aaron Alexander Burr
Adipocyte-Induced Inflammation In Prostate Tumor Progression In Bone: Role Of Cxcr2 And Osteopontin, Aimalie Lynnette Hardaway
The Therapeutic Targeting Of Folate Receptor Alpha Positive Tumors Via Folate Receptor Selective Novel 5- And 6- Substituted Pyrrolo [2,3-D]pyrimidine Antifolates", Shermaine Kimberly Mitchell-Ryan
Theses/Dissertations from 2014
The Tumor-Suppressive Role Of Secreted Maspin Via The Exosomes, Ivory Dean
Combating Resistance To Epidermal Growth Factor Recpetor Inhibitors In Triple Negative Breast Cancer, Julie Marie Madden
Tmprss2-Erg Regulation Of Androgen Biosynthetic Enzyme Expression, Dht Synthesis, And Androgen Receptor Activation In Prostate Cancer, Katelyn Ann Powell
Pathway Profiling Of Replicative And Induced Senescence, Maggie Purcell
Molecular Studies On The Anti-Tumor Effects Of Metal-Based Complexes: Involvement Of The Ubiquitin-Proteasome And Apoptotic Pathways, Sara M. Schmitt
A Novel Function For 12-Lipoxygenase In C-Met And Integrin β4 Axis Crosstalk, Elizabeth Tovar
Matriptase Mediated C-Met Signaling In Breast Cancer, Gina Lynn Zoratti
Theses/Dissertations from 2013
The Bca2 And Ampk Paradigm: Unraveling The Cancer Connection, Daniela (buac) Ventro
Expression And Regulation Of Map Kinase Phosphatases 1 And 2 In Breast Cancer Tamoxifen Sensitivity, Kelly Haagenson
Acidic Pericellular Ph: Effects On Proteolysis And Gene Expression As Determined In 3d Models Of Breast Carcinoma, Jennifer M. Rothberg
Impact Of Cryoablation On Tumor Immunity, Jesse Veenstra
Analysis Of The Structure And Function Of A Timp-1/cd63 Complex And Its Relationship To An Mt1-Mmp/cd63 Complex, Richard B. Warner
Theses/Dissertations from 2012
The proton-coupled folate transporter: biology and therapeutic applications to cancer, Sita Desmoulin
Role Of Thromboxane Receptor-Alpha In Prostate Cancer Progression, Prasanna Ekambaram
A Role For Reactive Oxygen Species In Photodynamic Therapy, Michael Price
Hdm2 Small-Molecule Inhibitors For Therapeutic Intervention In B-Cell Lymphoma, Angela Sosin
Theses/Dissertations from 2011
Amphiregulin (areg) And Epidermal Growth Factor (egf): Disparate In Egfr Signaling And Trafficking, Andrea Jacqueline Baillo
Functional in vitro analyses of lipid raft-associated cathepsin b: implication for the invasive phenotype of inflammatory breast cancer, Bernadette Caroline Victor
Theses/Dissertations from 2010
Matriptase/pdgf D/beta-Pdgfr Signaling Axis In Human Prostate Cancer: The Role Of Pten In The Regulation Of Pdgf D Expression, M. Katie Conley-Lacomb
Regulatory And Functional Aspects Of Foxo3a Transcription Factor And Their Implications In Prostate Cancer, Melissa Elise Dobson
Molecular Mechanisms Of Pressure-Stimulated Cancer Cell Signaling, Christina Downey
Activation Of Tumor Cell Death Program By Targeting The Ubiquitin-Proteasome Pathway: Significance In Cancer Treatment And Prevention, Michael Joseph Frezza
Molecular And Therapeutic Implications Of Notch1 Signaling In Pediatric T-Cell Acute Lymphoblastic Leukemia, Amanda Larson Gedman
Creg1 And Its Enhancement Of P16ink4a-Induced Senescence, Benchamart Moolmuang
Theses/Dissertations from 2000
Proteasome inhibitor induced apoptosis in THP-1 cells, Catheryne. Chen
Neutropenia : In Vitro Predictions of In Vivo Endpoints, Kristan A. Keyes
Regulation of arachidonate 12-lipoxygenase and its role in tumor cell alpoptosis, Keqin. Tang
Regulation of arachidonate 12-lipoxygenase and its role in tumor cell alpoptosis, Keqin. Tang
Differentiation of malignant human B-cell acute lymphoblastic leukemia, Nathan R. Wall
Theses/Dissertations from 1999
Rac1-induced invasion : intracellular proteolysis of the extracellular matrix, Mamoun. Ahram
Structural and functional relationship of a galactoside-binding protein---galectin-3, Hua Chang Gong
Tumor therapeutic response detected by nuclear magnetic resonance diffusion measurement, Zhanquan. He
Cathepsins B and D in human breast fibroblasts and epithelial/carcinoma cells, Jennifer E. Koblinski
Theses/Dissertations from 1998
Isolation and characterization of a common nuclear matrix protein and other studies, Tracy Sue Schwab
Theses/Dissertations from 1997
Absolute tumor perfusion determined by nuclear magnetic resonance spectroscopy :, Nicholas Edward Simpson